| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
OXOTREMORINE SESQUIFUMARATE manufacturers
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| | OXOTREMORINE SESQUIFUMARATE Basic information |
| Product Name: | OXOTREMORINE SESQUIFUMARATE | | Synonyms: | bis[1-[4-(pyrrolidin-1-yl)but-2-ynyl]pyrrolidin-2-one] trifumarate;OXOTREMORINESESQUIFUARATE;1-(4-[1-Pyrrolidinyl]-2-butynyl)-2-pyrrolidinone, 1-(4-[1-Pyrrolidinyl]2-butynyl)-2-pyrrolidinone;2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, (E)-2-butenedioate (2:3) (9ci);2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, fumarate (2:3) (8ci);2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, sesquifumarate;Einecs 241-388-3;1-[4-(1-PYRROLIDINYL)-2-BUTYNYL]-2-PYRROLIDINONE SESQUIFUMARATE | | CAS: | 17360-35-9 | | MF: | C36H48N4O14 | | MW: | 760.78 | | EINECS: | 241-388-3 | | Product Categories: | | | Mol File: | 17360-35-9.mol |  |
| | OXOTREMORINE SESQUIFUMARATE Chemical Properties |
| Melting point | 102-105 °C(lit.) | | storage temp. | 2-8°C | | solubility | H2O: 50 mg/mL | | form | powder | | color | off-white | | Water Solubility | H2O: >10mg/mL | | InChI | 1S/2C12H18N2O.3C4H4O4/c2*15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13;3*5-3(6)1-2-4(7)8/h2*1-2,5-11H2;3*1-2H,(H,5,6)(H,7,8)/b;;3*2-1+ | | InChIKey | WLYYOFJEBGHKEC-VQYXCCSOSA-N | | SMILES | [H]\C(=C(\[H])C(O)=O)C(O)=O.[H]\C(=C(\[H])C(O)=O)C(O)=O.[H]\C(=C(\[H])C(O)=O)C(O)=O.O=C1CCCN1CC#CCN2CCCC2.O=C3CCCN3CC#CCN4CCCC4 |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 28-36/37-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | UY6000000 | | HazardClass | 6.1(a) | | PackingGroup | I | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 1 Inhalation
Acute Tox. 2 Dermal
Acute Tox. 2 Oral | | Toxicity | LD50 ipr-mus: 6500 mg/kg TXAPA9 28,227,1974 |
| | OXOTREMORINE SESQUIFUMARATE Usage And Synthesis |
| Uses | Oxotremorine Sesquifumarate is an M2 and M4 Muscarinic acetylcholine receptor agonist. Positive allosteric modulator used in the treatment of CNS disorders. | | Biological Activity | Muscarinic agonist. | | Biochem/physiol Actions | Oxotremorine sesquifumarate salt is a muscarinic acetylcholine receptor agonist with preference for the M2 receptor. | | Safety Profile | A poison by intraperitoneal and intravenous routes. When heated to decomposition it emits toxic vapors of NOx | | storage | Store at RT |
| | OXOTREMORINE SESQUIFUMARATE Preparation Products And Raw materials |
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