- Fenothiocarb
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2020-04-28
- CAS:62850-32-2
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 500 tons
- FENOTHIOCARB
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- $1.00
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2020-01-01
- CAS:62850-32-2
- Min. Order: 1KG
- Purity: 95-99%
- Supply Ability: 1ton
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| | Fenothiocarb Basic information |
| Product Name: | Fenothiocarb | | Synonyms: | bi-5452;dimethylcarbamothioicacids-(4-phenoxybutyl)ester;dimethyl-carbamothioicacis-(4-phenoxybutyl)ester;kco-3001;phenothiocarb;PANOCON;PANOCON(R);FENOTHIOCARB STANDARD | | CAS: | 62850-32-2 | | MF: | C13H19NO2S | | MW: | 253.36 | | EINECS: | 200-589-5 | | Product Categories: | | | Mol File: | 62850-32-2.mol |  |
| | Fenothiocarb Chemical Properties |
| Melting point | 40.5℃ | | Boiling point | 155 °C | | density | 1.1414 (rough estimate) | | vapor pressure | 1.6 x l0-5 Pa (23 °C) | | refractive index | 1.6800 (estimate) | | storage temp. | 0-6°C | | Water Solubility | 30 mg l-1 (20 °C) | | pka | -1.21±0.70(Predicted) | | BRN | 2125738 | | Henry's Law Constant | 5.3×102 mol/(m3Pa) at 25℃, Ebert et al. (2023) |
| Hazard Codes | Xn,N | | Risk Statements | 22-50 | | Safety Statements | 61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | RTECS | FD3825000 | | HS Code | 29309090 |
| | Fenothiocarb Usage And Synthesis |
| Description | Fenothiocarb is a thiocarbamate acaricide used to control eggs and young stages of various spider mites. It has a moderate aqueous solubility but is soluble in various organic solvents. It tends not to be persistent in soil or water systems. Based on its physical-chemical properties fenothiocarb is not expected to leach to groundwater. Ecotoxicity data is sparse but suggests moderate levels. Toxicity via the oral route is moderate to humans and no information on chronic risks have been found. | | Chemical Properties | Pure product is white crystal. m.p. 40~41℃, vapor pressure 0.166×10-3Pa (20℃), b.p. 155℃/2.67Pa, soluble in acetone, methanol, ethanol, cyclohexanone, xylene and other organic solvents, insoluble in water. Stable to heat and acid, slightly unstable to light and alkali.1 month storage at 40℃ without decomposition. | | Uses | Fenothiocarb is an acaricide used to control the eggs and young
stages of Panonychus citri, Panonychus ulmi and other Panonychus spp. | | Definition | ChEBI: Fenothiocarb is an aromatic ether. | | Production Methods | Fenothiocarb is commercially synthesised through the esterification of dimethylcarbamothioic acid with 4-phenoxybutanol. The process begins with the preparation of the carbamothioic acid derivative, which is then reacted with 4-phenoxybutanol in the presence of a suitable catalyst or base, such as triethylamine, under controlled temperature and anhydrous conditions. The reaction typically occurs in an organic solvent like toluene or xylene to facilitate solubility and yield. | | Mechanism of action | Non-systemic. Disrupts the nervous system of insects, leading to paralysis and ultimately their death. | | Metabolic pathway | When the red mite, applied with 14C-fenothiocarb by
the contact method, metabolizes fenothiocarb,
resulting in several metabolites via the primary
oxidation of the N-methyl moiety. The
photodegradation of fenothiocarb on silica gel plate
exposed to sunlight gives rise to several degradation products. A primary photochemical reaction seems to
be the oxidation of the sulfur atom to form its
sulfoxide. Under greenhouse conditions, when
fenothiocarb is applied to the citrus trees, the major
metabolites identified in the leaves, rinds, and edible
fruit are 6-O-malonyl-b-D-glucosode of N-
hydroxymethyl fenothiocarb, N-formylfenothiocarb, and
glucoside conjugate of phenol (not shown in the map),
respectively. In soils, fenothiocarb is more rapidly
degraded under upland conditions than under flooded
conditions. Main degradation pathways include
oxidation of the sulfur atom which results in the
formation of methyl-4-phenoxybutylsulfoxide, its
sulfone, and 4-phenoxybutylsulfonic acid. | | Degradation | Fenothiocarb has long residual activity. It is stable to hydrolysis for 5 days
(pH 5-9, 40 °C) but it is decomposed slowly by sunlight (PM). [U-14C-phenyl]Fenothiocarb
was applied to the origin of silica gel TLC plates and
exposed to sunlight in September or October. The plates were developed,
with authentic standard compounds also applied, in two dimensions
using different solvent systems. After 72 hours exposure to sunlight, 34%
of parent fenothiocarb remained (DT50 45 hours). Twelve photoproducts
were detected. Products that were identified are illustrated in Scheme 1
and were N-formyl-fenothiocarb (2), desmethyl-fenothiocarb (3) the
bis(4-phenoxybutyl) thiolsulfinate (4), the bis(4-phenoxybutyl) thiolsulfonate
(5), the sulfoxide derivative (6) and 4-phenoxybutanesulfonic
acid (7). The latter two compounds were major products. The primary
photochemical reaction was oxidation of sulfur to form fenothiocarb
sulfoxide (6) followed by cleavage of the ester linkage and the oxidation
or dimerisation of the 4-phenoxybutanesulfenic acid intermediate. The
second main route of photodegradation was oxidation of the N-methyl
moiety of fenothiocarb (Unai and Tomiwaza, 1986b). | | Pesticide Type | Acaricide; Insecticide |
| | Fenothiocarb Preparation Products And Raw materials |
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