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| | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT) Basic information |
| Product Name: | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT) | | Synonyms: | MYELIN BASIC PROTEIN (87-99), GUINEA PIG, HUMAN;MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT);VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO;VHFFKNIVTPRTP;MBP (HUMAN, BOVINE, RAT);MBP (87-99) HUMAN;H-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH;H-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH (HUMAN, BOVINE, RAT) | | CAS: | 118506-26-6 | | MF: | C74H114N20O17 | | MW: | 1555.82 | | EINECS: | | | Product Categories: | Alzheimer;Peptide | | Mol File: | 118506-26-6.mol |  |
| | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT) Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | solubility | ≥15.97 mg/mL in EtOH with gentle warming and ultrasonic; ≥50.7 mg/mL in H2O; ≥77.8 mg/mL in DMSO | | form | solid | | pka | 3.39±0.20(Predicted) | | Water Solubility | Soluble to 2 mg/ml in water | | Sequence | Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro |
| | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT) Usage And Synthesis |
| Uses | Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2]. | | storage | Store at -20°C | | References | [1] R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12. DOI:10.1016/0165-5728(92)90004-5
[2] George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42. DOI:10.1021/jm800891n |
| | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT) Preparation Products And Raw materials |
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