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19(R)-Hydroxy prostaglandin f2alpha

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19(R)-Hydroxy prostaglandin f2alpha Basic information
Product Name:19(R)-Hydroxy prostaglandin f2alpha
Synonyms:9ALPHA,11ALPHA,15S,19R-TETRAHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;19(R)-hydroxy Prostaglandin F2α;UBWZMPMLSDJDSU-OQRQNLQMSA-N;Prosta-5,13-dien-1-oic acid, 9,11,15,19-tetrahydroxy-, (5Z,9α,11α,13E,15S,19R)-;19(R)-Hydroxy prostaglandin f2alpha
CAS:64625-53-2
MF:C20H34O6
MW:370.48
EINECS:
Product Categories:
Mol File:64625-53-2.mol
19(R)-Hydroxy prostaglandin f2alpha Structure
19(R)-Hydroxy prostaglandin f2alpha Chemical Properties
solubility 10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml
Safety Information
MSDS Information
19(R)-Hydroxy prostaglandin f2alpha Usage And Synthesis
Description19(R)-hydroxy PGF is an ω-1 hydroxylase metabolite of PGF found in human semen. The concentration of 19(R)-hydroxy PGF compounds (F and F together) in fresh human semen is about 20 μg/ml.1 19(R)-hydroxy PGF exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.2
Uses19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.
DefinitionChEBI: 19R-Hydroxy-PGF2alpha is a prostanoid.
References1. Taylor, P.L., and Kelly, R.W. The occurrence of 19-hydroxy F prostaglandins in human semen FEBS Lett. 57(1),22-25(1975).
2. Woodward, D.F., Protzman, C.E., Krauss, A.H.P., et al. Identification of 19(R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist Prostaglandins 46(4),371-383(1993).
19(R)-Hydroxy prostaglandin f2alpha Preparation Products And Raw materials
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(+-)-PGF2-alpha Dinoprost tromethamine 19(R)-Hydroxy prostaglandin f2alpha 11-Deoxy prostaglandin f2alpha 1,9alpha, 11alpha, 15S-tetrahydroxyprosta-5z, 13e-diene (15R)-BiMatoprost