11-DEOXY PROSTAGLANDIN F2ALPHA manufacturers
- 11-deoxy-PGF2a
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- $199.00
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2026-07-17
- CAS:37786-06-4
- Purity:
- Supply Ability: 10g
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| | 11-DEOXY PROSTAGLANDIN F2ALPHA Basic information |
| Product Name: | 11-DEOXY PROSTAGLANDIN F2ALPHA | | Synonyms: | 9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;11-DEOXY PROSTAGLANDIN F2ALPHA;11-deoxy Prostaglandin F2α;1-deoxy Prostaglandin F2α;YRFLKMLJQWGIIZ-APRRXLQMSA-N;1-deoxy Prostaglandin F2alpha;11-deoxy-Prostaglandin F2a;11-deoxy PGF2a | | CAS: | 37786-06-4 | | MF: | C20H34O4 | | MW: | 338.48 | | EINECS: | | | Product Categories: | | | Mol File: | 37786-06-4.mol |  |
| | 11-DEOXY PROSTAGLANDIN F2ALPHA Chemical Properties |
| Boiling point | 511.4±45.0 °C(Predicted) | | density | 1.090±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a) | | pka | 4.76±0.10(Predicted) |
| | 11-DEOXY PROSTAGLANDIN F2ALPHA Usage And Synthesis |
| Description | 11-deoxy PGF2α is a synthetic analog of PGF2α. It is a more potent agonist than PGF2α at inducing smooth muscle contractions of rabbit aorta, dog saphenous vein, and guinea pig trachea. It is approximately 20% less potent than U-46619. | | Uses | 11-Deoxyprostaglandin F2α is an activator for TREK-2 channels with EC50 of 0.294 μM. 11-Deoxyprostaglandin F2α inhibits the K2P channel TREK-1[1]. | | References | [1] Dadi PK,et al., Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx. ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. DOI:10.1021/acschemneuro.6b00301 |
| | 11-DEOXY PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials |
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Tag:11-DEOXY PROSTAGLANDIN F2ALPHA(37786-06-4)
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