Azido-PEG12-NHS ester manufacturers
- Azido-PEG12-NHS ester
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- $78.00 / 5mg
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2026-02-25
- CAS:2363756-50-5
- Min. Order:
- Purity: 98.16%
- Supply Ability: 10g
- N3-PEG12-NHS
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- $0.00 / 1g
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2026-02-05
- CAS:2363756-50-5
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- azido-PEG12-NHS ester
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- $0.00 / 1g
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2025-06-07
- CAS:2363756-50-5
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | Azido-PEG12-NHS ester Basic information |
| Product Name: | Azido-PEG12-NHS ester | | Synonyms: | Azido PEG12 NHS ester,Azido-PEG-12-NHS ester,PROTAC Linkers,Inhibitor,AzidoPEG12NHS ester,inhibit;Azido-PEG12-NHS eater;N3-PEG12-CH2CH2COONHS | | CAS: | 2363756-50-5 | | MF: | C31H56N4O16 | | MW: | 740.8 | | EINECS: | | | Product Categories: | | | Mol File: | 2363756-50-5.mol |  |
| | Azido-PEG12-NHS ester Chemical Properties |
| storage temp. | -20°C, sealed storage, away from moisture | | solubility | Soluble in DMSO, DCM, DMF | | form | Solid-Liquid Mixture | | color | White to off-white |
| | Azido-PEG12-NHS ester Usage And Synthesis |
| Description | Azido-PEG12-NHS ester is a aqueous soluble crosslinker containing an azide group and an NHS ester. Ne azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | | Uses | Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG12-NHS ester Preparation Products And Raw materials |
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