(S)-1-(4-氟苯基)-1-(2-(哌嗪-1-基)嘧啶-5-基)乙胺 基本信息
| 中文名称 | (S)-1-(4-氟苯基)-1-(2-(哌嗪-1-基)嘧啶-5-基)乙胺 |
|---|---|
| 中文同义词 | (S)-1-(4-氟苯基)-1-(2-(哌嗪-1-基)嘧啶-5-基)乙胺;阿伐普替尼杂质 |
| 英文名称 | 5-Pyrimidinemethanamine, α-(4-fluorophenyl)-α-methyl-2-(1-piperazinyl)-, (αS)- |
| 英文同义词 | 5-Pyrimidinemethanamine, α-(4-fluorophenyl)-α-methyl-2-(1-piperazinyl)-, (αS)-;(αS)-α-(4-Fluorophenyl)-α-methyl-2-(1-piperazinyl)-5-pyrimidinemethanamine;5-Pyrimidinemethanamine, α-(4-fluorophenyl)-α-methyl-2-(1-piperazinyl)-, (αS)-;(S)-1-(4-fluorophenyl)-1-(2-(piperazin-1-yl)pyrimidin-5-yl)ethanamine;(S)-1-(4-fluorophenyl)-1-(2-(piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine;Avapritinib Impurity |
| CAS号 | 1704492-14-7 |
| 分子式 | C16H20FN5 |
| 分子量 | 301.37 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1704492-14-7.mol |
| 结构式 |  |
(S)-1-(4-氟苯基)-1-(2-(哌嗪-1-基)嘧啶-5-基)乙胺 性质
| 沸点 | 485.5±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.211±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 8.69±0.10(Predicted) |
| InChI | InChI=1/C16H20FN5/c1-16(18,12-2-4-14(17)5-3-12)13-10-20-15(21-11-13)22-8-6-19-7-9-22/h2-5,10-11,19H,6-9,18H2,1H3/t16-/s3 |
| InChIKey | AXWNAQHKNUHLGI-QEIABERDNA-N |
| SMILES | [C@@](C1C=CC(F)=CC=1)(C1=CN=C(N2CCNCC2)N=C1)(N)C |&1:0,r| |