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| | 4,4'-Cyclohexylidenemethylenediphenol Basic information |
| Product Name: | 4,4'-Cyclohexylidenemethylenediphenol | | Synonyms: | 4,4'-DIHYDROXY BENZHYDRYLIDENE CYCLOHEXANE;F 6060;Cyclofenildiphenol, 4,4-Cyclohexylidenemethylenediphenol;4-[cyclohexylidene(4-hydroxyphenyl)methyl]phenol;4,4'-(Cyclohexylidenemethylene)bisphenol;4-[Cyclohexylidene(p-hydroxyphenyl)methyl]phenol;4,4'-Cyclohexylidenemethylenediphenol;Phenol, 4,4'-(cyclohexylidenemethylene)bis- | | CAS: | 5189-40-2 | | MF: | C19H20O2 | | MW: | 280.36 | | EINECS: | 225-972-5 | | Product Categories: | | | Mol File: | 5189-40-2.mol |  |
| | 4,4'-Cyclohexylidenemethylenediphenol Chemical Properties |
| Melting point | 235-236 °C(Solv: ethanol (64-17-5); ligroine (8032-32-4)) | | Boiling point | 462.8±25.0 °C(Predicted) | | density | 1.180±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 9.83±0.30(Predicted) |
| | 4,4'-Cyclohexylidenemethylenediphenol Usage And Synthesis |
| Uses | 4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetric cyclic nonsteroidal estrogen. 4,4'-(Cyclohexylidenemethylene)diphenol has high binding affinity for estrogen receptors ERα and ERβ[1]. | | IC 50 | ERα; ERβ | | References | [1] Kieser KJ, et al. Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs). J Med Chem. 2010 Apr 22;53(8):3320-9. DOI:10.1021/jm100047k |
| | 4,4'-Cyclohexylidenemethylenediphenol Preparation Products And Raw materials |
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