3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate

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3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate manufacturers

3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate Basic information
Product Name:3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate
Synonyms:3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate;Bisacrylic acid 3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester;Bispropenoic acid 3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester;Einecs 285-782-3;2-Propenoic acid, 1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl) ester;Bis-acrylate-PEG6;2-Propenoic acid,1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl) ester;2-Propenoic acid, 3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester
CAS:85136-58-9
MF:C18H30O9
MW:390.4254
EINECS:2857823
Product Categories:
Mol File:85136-58-9.mol
3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate Structure
3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate Chemical Properties
storage temp. 2-8°C, stored under nitrogen
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate Usage And Synthesis
UsesBis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological ActivityBis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50PEGs
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
3,6,9,12,15-pentaoxaheptadecane-1,17-diyl diacrylate Preparation Products And Raw materials
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