- Sudoxicam
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- $58.00
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2026-06-02
- CAS:34042-85-8
- Purity: 99.93%
- Supply Ability: 10g
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| | sudoxicam Basic information |
| Product Name: | sudoxicam | | Synonyms: | 4-Hydroxy-2-methyl-3-(2-thiazolylcarbamoyl)-2H-1,2-benzothiazine 1,1-dioxide;4-Hydroxy-2-methyl-N-(thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;CP-15973;4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1$l^{6},2-benzothiazine-3-carboxamide;2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-thiazolyl-, 1,1-dioxide;Sudoxicam, 10 mM in DMSO;4-HYDROXY-2-METHYL-N-(1,3-THIAZOL-2-YL)-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE | | CAS: | 34042-85-8 | | MF: | C13H11N3O4S2 | | MW: | 337.379 | | EINECS: | 2518087 | | Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds | | Mol File: | 34042-85-8.mol |  |
| | sudoxicam Chemical Properties |
| Melting point | 240-243°C (dec.) | | storage temp. | Refrigerator | | solubility | DMSO : 83.33 mg/mL (247.00 mM; ultrasonic and warming and heat to 80°C) | | form | Solid | | color | Brown |
| | sudoxicam Usage And Synthesis |
| Chemical Properties | Brown Solid | | Uses | Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class. | | in vivo | Sudoxicam (1-10 mg/kg; oral administration; daily; for 7 days; rats) treatment effective reduces plasma inflammation units, reduces the swelling of inflamed hind-paws and restores toward normal the daily gain in body weight[2].
In the intact rat, Sudoxicam significantly inhibited edema formation at doses as low as 0.1 mg/kg, p.o[2].
Sudoxicam inhibits the erythema caused by ultraviolet irradiation in the guinea pig.
Sudoxicam (3.3 mg/kg, i.p.) is capable of counteracting the pyrexia induced by the intraperitoneal injection of typhoid/paratyphoid vaccine in rats, maintaining body temperature about that of uninjected control rats[2].
The plasma half-life of Sudoxicam ranged between 8 hours (monkey), 13 hours (rat), and 60 hours (dog)[2]. | Animal Model: | Rats injected with ,i>M. butyrieum[2] | | Dosage: | 1 mg/kg, 3.3 mg/kg, 10 mg/kg | | Administration: | Oral administration; daily; for 7 days | | Result: | Were both effective in reducing plasma inflammation units, in reducing the swelling of inflamed hind-paws.
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| | sudoxicam Preparation Products And Raw materials |
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