- Kahweol
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- $54.00 / 1mg
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2025-09-30
- CAS:6894-43-5
- Min. Order:
- Purity: 99.26%
- Supply Ability: 10g
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| | KAHWEOL Basic information |
| Product Name: | KAHWEOL | | Synonyms: | 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;KAHWEOL;(3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;[3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;KAHWEOL USP/EP/BP;Kahweol
DISCONTINUED, unstable;Kahweol-RM;Kahweol, Diterpene molecule in coffee beans | | CAS: | 6894-43-5 | | MF: | C20H26O3 | | MW: | 314.42 | | EINECS: | | | Product Categories: | Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 6894-43-5.mol |  |
| | KAHWEOL Chemical Properties |
| Melting point | 88-90℃ | | Boiling point | 476.6±45.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM) | | pka | 14.43±0.40(Predicted) | | form | White to off-white solid. | | color | Off-white to light yellow | | LogP | 3.380 (est) |
| | KAHWEOL Usage And Synthesis |
| Uses | Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation. | | Definition | ChEBI: Kahweol is a diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. It has a role as an angiogenesis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a diterpenoid, a member of furans, an organic heteropentacyclic compound, a tertiary alcohol and a primary alcohol. |
| | KAHWEOL Preparation Products And Raw materials |
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