L 741626

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  • L-741626
  • L-741626 pictures
  • $30.00
  • 2026-06-02
  • CAS:81226-60-0
  • Purity: 98.90%
  • Supply Ability: 10g
L 741626 Basic information
Product Name:L 741626
Synonyms:3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL;receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit;4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-;L-741,626, D2 antagonist;L-741626, 10 mM in DMSO
CAS:81226-60-0
MF:C20H21ClN2O
MW:340.85
EINECS:
Product Categories:
Mol File:81226-60-0.mol
L 741626 Structure
L 741626 Chemical Properties
Boiling point 548.8±50.0 °C(Predicted)
density 1.311±0.06 g/cm3(Predicted)
storage temp. room temp
solubility DMSO: ≥20mg/mL
form powder
pka13.87±0.20(Predicted)
color white to beige
InChI1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2
InChIKeyLLBLNMUONVVVPG-UHFFFAOYSA-N
SMILESOC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
L 741626 Usage And Synthesis
UsesL-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists.
UsesL-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
DefinitionChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines.
HazardA poison.
Biochem/physiol ActionsL-741,626 is a selective dopamine (D2) receptor antagonist.
storageStore at RT
L 741626 Preparation Products And Raw materials
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