5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione

5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Suppliers list
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5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione manufacturers

  • L 152804
  • L 152804 pictures
  • $43.00
  • 2026-04-22
  • CAS:6508-43-6
  • Purity: 99.82%
  • Supply Ability: 10g
5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Basic information
Product Name:5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione
Synonyms:L-152,804;5,5-Mmethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-1,3 cyclohexanedione;9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone;1,3-Cyclohexanedione, 5,5-dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-;2-(3,3-Dimethyl-1-oxo-2,3,4,9-tetrahydro-1H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione;L 152804, 10 mM in DMSO;(S,S)-BRL-37344 sodium;5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione
CAS:6508-43-6
MF:C23H26O4
MW:366.45
EINECS:
Product Categories:Neuropeptide Y (NPY ) receptor
Mol File:6508-43-6.mol
5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Structure
5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Chemical Properties
Melting point 207-208 °C
Boiling point 513.7±50.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
storage temp. Desiccate at +4°C
solubility DMSO: soluble5mg/mL, clear (warmed)
form powder
pka4.86±0.42(Predicted)
color white to beige
Safety Information
Hazard Codes T,N
Risk Statements 25-50/53
Safety Statements 45-60-61
RIDADR UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany 3
MSDS Information
5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Usage And Synthesis
UsesL-152,804 is a potent and orally available Y5 antagonist, which is the receptor postulated to be responsible for hypothalamic "feeding".
DefinitionChEBI: 2-(3,3-dimethyl-1-oxo-4,9-dihydro-2H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione is a member of xanthenes.
Biological ActivityPotent, selective non-peptide neuropeptide Y Y 5 receptor antagonist (K i = 26 nM for hY 5 ). Displays > 300-fold selectivity over hY 1 , hY 2 , and hY 4 receptors. Causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Centrally active upon oral administration in vivo .
IC 50NPY Y5 receptor
storageDesiccate at +4°C
5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione Preparation Products And Raw materials
Tag:5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1OXO-1H-xanthen-9-yl)-1,3-cyclohexanedione(6508-43-6) Related Product Information
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