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| | aspidin BB Basic information |
| Product Name: | aspidin BB | | Synonyms: | aspidin BB;2-[[2,6-Dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-2,5-cyclohexadien-1-one;2,5-Cyclohexadien-1-one, 2-[[2,6-dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)- | | CAS: | 584-28-1 | | MF: | C25H32O8 | | MW: | 460.52 | | EINECS: | | | Product Categories: | | | Mol File: | 584-28-1.mol |  |
| | aspidin BB Chemical Properties |
| Melting point | 124-125° | | Boiling point | 661.2±55.0 °C(Predicted) | | density | 1.285±0.06 g/cm3(Predicted) | | pka | 4.50±1.00(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | aspidin BB Usage And Synthesis |
| Uses | Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells[1][2]. | | Definition | ChEBI: Aspidin is a carboxylic ester. It is functionally related to a phloroglucinol. | | IC 50 | Bcl-2; Bax; Caspase-3 | | References | [1] Sun Y, et al. Aspidin BB, a phloroglucinol derivative, induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. Chem Biol Interact. 2013 Jul 5;204(2):88-97. DOI:10.1016/j.cbi.2013.04.008
[2] Chen NH, et al. Drychampones A-C: Three Meroterpenoids from Dryopteris championii. J Org Chem. 2016 Oct 7;81(19):9443-9448. DOI:10.1021/acs.joc.6b01720 |
| | aspidin BB Preparation Products And Raw materials |
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