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| | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Basic information |
| Product Name: | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride | | Synonyms: | Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride;Nsc145378;trans-4-AMino-cyclohexanecarboxylic acid Methyl ester hydrochloride;Trans-Methyl 4-aMinocyclohexanecarboxylate HCl;trans-4-AMino-cyclohexanecarboxylic acid Methyl ester;trans-Methyl 4-aMinocyclohexanecarboxylate hydrochloride;(1r,4r)-Methyl 4-(6-(pyrrolidin-1-yl)pyriMidin-4-ylaMino)cyclohexanecarboxylate;(1r,4r)-Methyl 4-aMinocyclohexanecarboxylate hydrochloride | | CAS: | 61367-07-5 | | MF: | C8H16ClNO2 | | MW: | 193.67 | | EINECS: | | | Product Categories: | 61367-07-5 | | Mol File: | 61367-07-5.mol |  |
| | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Chemical Properties |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | color | White to Almost white | | Water Solubility | Soluble in water. | | InChI | InChI=1/C8H15NO2.ClH/c1-11-8(10)6-2-4-7(9)5-3-6;/h6-7H,2-5,9H2,1H3;1H/t6-,7-; | | InChIKey | NHAYDXCUCXRAMF-MEZFUOHNNA-N | | SMILES | C([C@@H]1CC[C@@H](N)CC1)(=O)OC.Cl |&1:1,4,r| |
| | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Uses | Methyl trans-4-aminocyclohexanecarboxylate hydrochloride is generally used as a intermediate in pharmaceutical and chemical research. | | Reactions |
Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride can react with strong oxidizing agents.
| | Hazard | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride can cause serious eye damage/eye irritation.
| | Synthesis | (Trans)-4-aminocyclohexanecarboxylic acid (200 mg, 1.40 mmol) was suspended in MeOH (5.5 mL) and cooled to -10 ℃. To this was added SOCl2 (204 μL, 2.79 mmol) dropwise, and the mixture was stirred for 15 minutes. The reaction mixture was warmed to ambient temperature for 15 minutes, followed by heating at reflux for 1 hour. After cooling, the mixture was concentrated to afford Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride (260 mg, 96.1 % yield).
| | References | [1] Patent: WO2011/6074, 2011, A1. Location in patent: Page/Page column 95 |
| | Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Preparation Products And Raw materials |
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