- 2-Ethyl-3-methylpyrazine
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- $31.00 / 1kg
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2025-09-25
- CAS:15707-23-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 2-Ethyl-3-methylpyrazine Basic information |
| | 2-Ethyl-3-methylpyrazine Chemical Properties |
| Boiling point | 57 °C10 mm Hg(lit.) | | density | 0.987 g/mL at 25 °C | | vapor pressure | 1.74hPa at 20℃ | | refractive index | n20/D 1.503(lit.) | | FEMA | 3155 | 2-ETHYL-3-METHYLPYRAZINE | | Fp | 138 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | sparingly soluble | | pka | 1.94±0.10(Predicted) | | Specific Gravity | 0.987 | | color | Colorless to Light yellow | | Odor | at 0.10 % in dipropylene glycol. nutty peanut musty corn raw earthy bread | | Odor Type | nutty | | biological source | synthetic | | Water Solubility | sparingly soluble | | JECFA Number | 768 | | BRN | 956775 | | Major Application | flavors and fragrances | | Cosmetics Ingredients Functions | PERFUMING | | InChI | 1S/C7H10N2/c1-3-7-6(2)8-4-5-9-7/h4-5H,3H2,1-2H3 | | InChIKey | LNIMMWYNSBZESE-UHFFFAOYSA-N | | SMILES | CCc1nccnc1C | | LogP | 1.42 at 25℃ | | CAS DataBase Reference | 15707-23-0(CAS DataBase Reference) | | NIST Chemistry Reference | Pyrazine, 2-ethyl-3-methyl-(15707-23-0) | | EPA Substance Registry System | Pyrazine, 2-ethyl-3-methyl- (15707-23-0) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-24/25 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | RTECS | UQ3335000 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29339900 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| | 2-Ethyl-3-methylpyrazine Usage And Synthesis |
| Chemical Properties | clear colorless to slightly yellow liquid | | Chemical Properties | 2-Ethyl-3-methylpyrazine has a strong, raw-potato, roasted, earthy odor. | | Occurrence | Reported found in bakery products, roasted barley, coffee, peanuts, filberts, potato products, soy products,
roasted and fried chicken, beef, pork, beer, rum, cocoa, coffee, tea, malt, shrimp and crayfish. | | Uses | 2-Ethyl-3-methylpyrazine is used in preparation of Chinese chestnut pyrolyzate and their application to e-cigarette. | | Uses | Food additive. | | Definition | ChEBI: 2-Ethyl-3-methylpyrazine, 9CI is a member of pyrazines. | | Preparation | By condensation of ethylenediamine with 2,3-pentanedione. | | Aroma threshold values | Detection: 2 ppm (130 ppb in water) | | Taste threshold values | Taste characteristics at 10 ppm: nutty, peanut, musty corn-like with raw and oily nuances. | | Hazard | Moderately toxic by ingestion. | | Flammability and Explosibility | Not classified | | Safety Profile | Moderately toxic by
ingestion. When heated to decomposition it
emits acrid smoke and irritating fumes. | | Synthesis | 2,3-Pentanedione, ethylenediamine and anhydrous ethanol were mixed in a three-necked flask at -5 to 3°C in a mass ratio of 1:1.1:70 and the reaction was stirred for 7 hours. After completion of the reaction, the system was slowly warmed to room temperature and stirring was continued for 3 hours. Subsequently, the temperature was raised to 65-70°C and refluxed for 4 hours. After the reaction mixture was cooled to 30-40 °C, xylene and potassium hydroxide catalyst was added to a three-necked flask, where the mass ratio of 2,3-pentanedione, potassium hydroxide to xylene was 1:0.8:2.8. Heating was continued to 65-70 °C and refluxed for 5 h. The reaction mixture was then cooled to room temperature and stirred for 7 h. The reaction mixture was then cooled to room temperature and stirred for 4 h. After the reaction was completed, it was cooled to room temperature and subjected to filtration. The filtrate was distilled at atmospheric pressure and the resulting concentrate was extracted with saturated brine solution, the organic phases were combined and dried with anhydrous sodium sulfate. The dried organic phase was filtered and subjected to atmospheric pressure distillation to collect the 55-60 °C/1.33 kPa fraction to give 2-ethyl-3-methylpyrazine in more than 93.5% product yield. | | References | [1] Patent: CN107556250, 2018, A. Location in patent: Paragraph 0024; 0029; 0035; 0041; 0049; 0053 |
| | 2-Ethyl-3-methylpyrazine Preparation Products And Raw materials |
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