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| | Z-PHE-LEU-GLU-PNA Basic information |
| Product Name: | Z-PHE-LEU-GLU-PNA | | Synonyms: | Z-PHE-LEU-GLU-PNA;Z-FLE-PNA;(4S)-4-[[(2S)-4-methyl-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoyl]amino]-5-(4-nitroanilino)-5-oxopentanoic acid;L-α-Glutamine, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-L-leucyl-N-(4-nitrophenyl)- | | CAS: | 104634-10-8 | | MF: | C34H39N5O9 | | MW: | 661.7 | | EINECS: | | | Product Categories: | | | Mol File: | 104634-10-8.mol |  |
| | Z-PHE-LEU-GLU-PNA Chemical Properties |
| Boiling point | 1004.4±65.0 °C(Predicted) | | density | 1.304±0.06 g/cm3(Predicted) | | pka | 4.42±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Z-Phe-Leu-{Glu-pNA} |
| | Z-PHE-LEU-GLU-PNA Usage And Synthesis |
| Uses | Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer[1][2]. | | References | [1] Wei Ye, et al. Characterization of the glutamate-specific endopeptidase fromBacillus licheniformisexpressed inEscherichia coli. J Biotechnol. 2013 Oct 10;168(1):40-5. DOI:10.1016/j.jbiotec.2013.08.009
[2] Wei Ye, et al. A new strategy for recovery of two peptides without Glu employing glutamate-specific endopeptidase from Bacillus licheniformis. Enzyme Microb Technol. 2014 Jan 10:54:25-31. DOI:10.1016/j.enzmictec.2013.09.013 |
| | Z-PHE-LEU-GLU-PNA Preparation Products And Raw materials |
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