Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride

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Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride Basic information
Product Name:Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride
Synonyms:PROTEASOME SUBSTRATE IV (FLUOROGENIC);N-CBZ-VAL-LYS-MET 7-AMIDO-4-METHYLCOUMARIN;Z-VKM-AMC;Z-VAL-LYS-MET-AMC;Z-VAL-LYS-MET-AMC ACETATE SALT;Z-VAL-LYS-MET-MCA HYDROCHLORIDE;z-val-lys-met 7-amido-4-methylcoumarin;Z-VAL-LYS-MET-MCA
CAS:141223-71-4
MF:C34H45N5O7S
MW:667.82
EINECS:
Product Categories:Amyloid A4-generating enzymes;Amyloid A4-generating enzymesEnzyme Substrates;Enzyme Substrates;Protease Substrates;Substrates by Enzyme
Mol File:141223-71-4.mol
Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride Structure
Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride Chemical Properties
Boiling point 966.2±65.0 °C(Predicted)
density 1.245±0.06 g/cm3(Predicted)
storage temp. −20°C
pka11.05±0.46(Predicted)
SequenceZ-Val-Lys-{Met-AMC}
Safety Information
WGK Germany 3
MSDS Information
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SigmaAldrich English
Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride Usage And Synthesis
UsesFluorogenic Proteasome Substrate (Z-VKM-AMC) is used to measure the peptidase activity of the 20S proteasome. Also used as a fluorogenic substrate for Alzheimer''s Disease amyloid A4-generating enzymes. AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.
Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride Preparation Products And Raw materials
Tag:Benzyloxycarbonyl-L-valyl-L-lysyl-L-methionine 4-methylcoumaryl-7-amide hydrochloride(141223-71-4) Related Product Information
Z-Val-Val-Arg-AMC Z-Val-Leu-Arg-4MβNA · HCl Z-VEID-AFC UROKINASE SUBSTRATE I, COLORIMETRIC Z-Tyr-Ser-OH Z-Val-Ala-Asp-AMC Z-Lys-Arg-PNA 2 HCl Z-Tyr-Val-Ala-Asp-chloromethylketone Z-Phe-PNA Z-Val-Phe-OH Z-VDVAD-AFC Z-YVAD-AFC Z-Val-Ala-Asn-AMC Z-Val-Lys-Lys-Arg-AFC Z-Phe-Leu-Glu-PNA Z-Val-Lys-Lys-Arg-4m-betana hydrochloride salt Z-VRPR-FMK (trifluoroacetate salt) L-Alaninamide,N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-[(2,6-dichlorobenzoyl)oxy]-1-(2-ethoxy-2-oxoethyl)-2-oxopropyl]-(9CI)