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9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid

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9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid Basic information
Product Name:9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid
Synonyms:PROSTAGLANDIN F1BETA;DZUXGQBLFALXCR-JQXWHSLNSA-N;9BETA-PGF1ALPHA;Prost-13-en-1-oic acid, 9,11,15-trihydroxy-, (9β,11α,13E,15S)-;Prostaglandin F1β;Alprostadil (Prostaglandin E1) Impurity 12;Alprostadil (prostaglandin E1) impurity 19;PGF1β
CAS:10164-73-5
MF:C20H36O5
MW:356.5
EINECS:
Product Categories:
Mol File:10164-73-5.mol
9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid Structure
9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid Chemical Properties
Boiling point 526.5±50.0 °C(Predicted)
density 1.136±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >75 mg/ml; PBS pH 7.2: >2 mg/ml
form A crystalline solid
pka4.78±0.10(Predicted)
InChI1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18+,19+/m0/s1
InChIKeyDZUXGQBLFALXCR-JQXWHSLNSA-N
SMILESO[C@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid Usage And Synthesis
DescriptionPGF is the C-9 epimer of PGF. It was shown to enhance respiratory rate in experimental animals when administered intravenously.1
UsesProstaglandin F1β (PGF1β) is the C-9 epimer of 1α. Prostaglandin F1β increased the respiratory rate of rabbits[1].
DefinitionChEBI: PGF1beta is a prostanoid.
References1. Brookes, L.G., and Marshall, R.C. The effects of some prostaglandins on respiration in the rabbit J. Pharm. Pharmacol. 26(Suppl),80P-81P(1974).
9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid Preparation Products And Raw materials
Tag:9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid(10164-73-5) Related Product Information
9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid 11-Deoxy prostaglandin F1BeTa (5Z)-N-(Cyclopropylmethyl)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-5-heptenamide 8-iso Prostaglandin F1β 9beta-Tetranor-13,14-dihydro-15-keto prostaglandin F1BeTa 11BETA-PROSTAGLANDIN F1BETA