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| | MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER Basic information |
| | MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER Chemical Properties |
| storage temp. | −20°C | | form | Solid | | color | White to off-white | | α-end | methoxy | | Ω-end | NHS ester | | InChI | InChI=1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3 | | InChIKey | NYXRHTOXAYVBMV-UHFFFAOYSA-N | | SMILES | O(C(C([H])([H])OC([H])([H])C([H])([H])O[H])=O)N1C(C([H])([H])C([H])([H])C1=O)=O.O(C([H])([H])[H])C([H])([H])C([H])([H])O[H] |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 3-10-23 | | Storage Class | 11 - Combustible Solids |
| | MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER Usage And Synthesis |
| Uses | m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. | | References | [1] Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3(2): 123-129. |
| | MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER Preparation Products And Raw materials |
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