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| | 7,8-Dihydro-8-oxoadenosine-3':5'-cyclic monophosphate Basic information |
| Product Name: | 7,8-Dihydro-8-oxoadenosine-3':5'-cyclic monophosphate | | Synonyms: | 8-hydroxyadenosine-3’,5’-cyclicmonophosphate,sodiumsalt(8-oh-camp);8-hydroxyadenosine3’:5’-cyclic*monophosphoricac;ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-HYDROXY-, SODIUM SALT;8-HYDROXYADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-HYDROXYADENOSINE 3':5'-CYCLIC MONOPHOSPHORIC ACID;8-OH-CAMP, NA;8-OH-CAMP SODIUM SALT;8-hydroxyadenosine 3':5'-cyclic monophosphate | | CAS: | 31356-95-3 | | MF: | C10H12N5O7P | | MW: | 345.21 | | EINECS: | | | Product Categories: | | | Mol File: | 31356-95-3.mol |  |
| | 7,8-Dihydro-8-oxoadenosine-3':5'-cyclic monophosphate Chemical Properties |
| density | 1.98±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 1.07±0.60(Predicted) |
| | 7,8-Dihydro-8-oxoadenosine-3':5'-cyclic monophosphate Usage And Synthesis |
| Uses | 8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases[1]. | | References | [1] Waidmann O, et al. Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8-(4-chlorophenylthio)-modified cAMP analogs and their hydrolytic products[J]. Journal of biological chemistry, 2009, 284(47): 32256-32263. DOI:10.1074/jbc.M109.056622 |
| | 7,8-Dihydro-8-oxoadenosine-3':5'-cyclic monophosphate Preparation Products And Raw materials |
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