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- Boc-NH-PEG8-OH
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2026-07-24
- CAS:1345337-22-5
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- BocNH-PEG8-OH
-
-
2026-01-29
- CAS:1345337-22-5
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 300kg
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| | Z-8-aMino-3,6-dioxaoctanoic acid Basic information |
| Product Name: | Z-8-aMino-3,6-dioxaoctanoic acid | | Synonyms: | Z-8-aMino-3,6-dioxaoctanoic acid;Z-NH-PEG2-CH2COOH;CBZ-8-aMino-3,6-dioxaoctanoic acid;23-(Boc-amino)-3,6,9,12,15,18,21-heptaoxa-1-tricosanol;NHBoc-PEG8-OH;CBZ-NH-PEG2-acetic acid;t-boc-N-amido-PEG8-alcohol;CAS_16545-06-8 | | CAS: | 1345337-22-5 | | MF: | C21H43NO10 | | MW: | 469.57 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1345337-22-5.mol |  |
| | Z-8-aMino-3,6-dioxaoctanoic acid Chemical Properties |
| Boiling point | 553.7±50.0 °C(Predicted) | | density | 1.093±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Viscous Liquid | | pka | 12.23±0.46(Predicted) | | color | Colorless to light yellow |
| | Z-8-aMino-3,6-dioxaoctanoic acid Usage And Synthesis |
| Description | N-Boc-PEG8-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Uses | N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Z-8-aMino-3,6-dioxaoctanoic acid Preparation Products And Raw materials |
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