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| | 4-AMino-2-chloro-1,3,5-triazine Basic information |
| Product Name: | 4-AMino-2-chloro-1,3,5-triazine | | Synonyms: | 4-AMino-2-chloro-1,3,5-triazine;2-Amino-4-chloro-1,3,5-triazine;1,3,5-Triazin-2-amine, 4-chloro-;4-Chloro-[1,3,5]triazin-2-ylamine;4-chloro-1,3,5-triazin-2-amine | | CAS: | 7709-13-9 | | MF: | C3H3ClN4 | | MW: | 130.54 | | EINECS: | | | Product Categories: | Metabolites & Impurities;Pharmaceuticals;Amines, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Intermediates & Fine Chemicals | | Mol File: | 7709-13-9.mol |  |
| | 4-AMino-2-chloro-1,3,5-triazine Chemical Properties |
| Boiling point | 383.3±25.0 °C(Predicted) | | density | 1.566±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Dichloromethane, Methanol | | pka | 2.62±0.10(Predicted) | | form | Solid | | color | White |
| | 4-AMino-2-chloro-1,3,5-triazine Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A metabolite of atrazine (A794600). | | Synthesis | General procedure for the synthesis of 4-chloro-1,3,5-triazin-2-amine from 2,4-dichloro-1,3,5-triazine: 2,4-dichloro-1,3,5-triazine (45 mg, 0.3 mmol) was added to 2 mL of aqueous NH4OH. The reaction mixture was stirred at -20 °C for 10 min, followed by filtration and washing with distilled water. The product was dried to afford 4-chloro-1,3,5-triazin-2-amine (18 mg, 46% yield) as a yellow solid, which could be used in subsequent reactions without further purification. Mass spectrometry (MS) analysis showed m/z: 131.0 ([M + H]+). | | References | [1] Patent: WO2014/15523, 2014, A1. Location in patent: Page/Page column 126; 127
[2] Patent: WO2014/15830, 2014, A1. Location in patent: Page/Page column 151
[3] Agricultural and Biological Chemistry, 1982, vol. 46, # 6, p. 1439 - 1445
[4] Patent: WO2011/146882, 2011, A1. Location in patent: Page/Page column 108
[5] Patent: WO2014/15675, 2014, A1. Location in patent: Page/Page column 151; 152 |
| | 4-AMino-2-chloro-1,3,5-triazine Preparation Products And Raw materials |
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