BV 6
| 中文名称 | BV 6 |
|---|---|
| 中文同义词 | BV-6游离态;化合物BV6;(2S,2'S)-N,N'-((2S,2'S)-(己烷-1,6-二基双(氮杂二基))双(1-氧代-3,3-二苯基丙烷-1,2-二基))双 (1-((S)-2-环己基-2-((S)-2-(甲基氨基)丙酰胺基)乙酰基)吡咯烷-2-甲酰胺);BV-6 三氟乙酸盐;化合物BV6,10 MM DMSO 溶液;BV6 拮抗剂;BV6试剂;BV6 拮抗剂 |
| 英文名称 | BV6 |
| 英文同义词 | 4,4'-(1,6-Hexanediyl)bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolyl-beta-phenyl-L-phenylalaninamide;BV6;N,N'-(hexane-1,6-diyl)bis(1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-L-prolyl-beta-phenyl-L-phenylalaninamide):trifluoroacetic acid(1:x);CHEBI:47924;CHEBI:47924; BV-6 BV 6;CS-2877;CS-1501;BV-6;BV6 |
| CAS号 | 1001600-56-1 |
| 分子式 | C70H96N10O8 |
| 分子量 | 1205.58 |
| EINECS号 | |
| 相关类别 | 小分子抑制剂，天然产物;抑制剂;Inhibitors |
| Mol文件 | 1001600-56-1.mol |
| 结构式 |  |
BV 6 性质
| 沸点 | 1376.7±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.177±0.06 g/cm3(Predicted) |
| 储存条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | DMSO 中≥60.28 mg/mL；不溶于水； ≥12.6 mg/mL，乙醇溶液（需要超声波） |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.89±0.20(Predicted) |
| 颜色 | 白色至米白色 |
| InChIKey | DPXJXGNXKOVBJV-YLOPQIBLSA-N |
IAP
Murine cIAP-1, cIAP-2 and XIAP expressions are clearly observed in the cytoplasm of both epithelial and stromal cells of implants, whereas Survivin is mainly expressed in the nuclei BV6 treatment for 4 weeks attenuated the intensity of IAPs expression. The size of lesions range from ~2 to 7 mm in diameter. The monolayer epithelial cell lining of the cyst is shown. After immunohistochemical staining, cytokeratin and vimentin are positively stained, whereas calretinin is negative. After BV6 treatment for 4 weeks, the total number of lesions (4.6 versus 2.8/mouse), the average weight (78.1 versus 32.0 mg/mouse) and the surface area (44.5 versus 24.6 mm 2 /mouse) of lesions are significantly less than in the controls. In the endometrial gland epithelia or stroma, the percentage of Ki67-positive cells decreases after BV6 treatment.
安全信息
| WGK Germany | WGK 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-16701 | BV6 | 1001600-56-1 | 1 mg | 453元 |
| 2026/09/15 | HY-16701 | BV 6 BV6 | 1001600-56-1 | 2mg | 621元 |