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| | Euphorbia factor L9 Basic information |
| Product Name: | Euphorbia factor L9 | | Synonyms: | Euphorbia factor L9;((2S,3S,4R,5R,7R,9S,11S,15R)-5,15-Diacetoxy-3-benzoyloxy-7-nicotinoyloxy-14-oxolathyra-6(17),12E-diene;3-Pyridinecarboxylic acid, (1aS,3R,5R,5aR,6S,7S,8aR,10E,11aR)-5,8a-bis(acetyloxy)-6-(benzoyloxy)-1a,2,3,4,5,5a,6,7,8,8a,9,11a-dodecahydro-1,1,7,10-tetramethyl-4-methylene-9-oxo-1H-cyclopenta[a]cyclopropa[f]cycloundecen-3-yl ester (9CI);Euphorbia factor L9 USP/EP/BP | | CAS: | 129393-28-8 | | MF: | C37H41NO9 | | MW: | 643.73 | | EINECS: | | | Product Categories: | | | Mol File: | 129393-28-8.mol |  |
| | Euphorbia factor L9 Chemical Properties |
| Melting point | 119-122 °C | | Boiling point | 702.7±60.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | pka | 3.09±0.10(Predicted) |
| | Euphorbia factor L9 Usage And Synthesis |
| Synthesis | A method for the preparation of EuphorbiaFactorL9 (EuphorbiaFactorL9), the specific steps are as follows:
(1) take Chijinzi (commercially purchased) as raw material, carry on pulverization to get Chijinzi powder;
(2)Take Chijinzi powder for organic reagent extraction, the organic reagent is ethyl acetate, collect the supernatant after extraction, filtration, concentration, drying;
(3) Repeat the precipitation obtained in step (2) for 1 to 5 times of extraction, collect the supernatant after extraction, filter, concentrate and dry to obtain the QJZ primary extract;
(4) take the QJZ primary extract obtained in step (3) to dissolve all with the mobile phase, said mobile phase is mobile phase A or mobile phase B or a combination of the two, the separation is carried out by the preparative liquid phase DAC normal-phase chromatographic column (one-dimensional liquid chromatography), and the separation is carried out by using the binary mobile phase system for elution, and the combination of n-hexane, ethanol, or one or a combination of one or several kinds of said mobile phase A and mobile phase B is used, and the elution mode is gradient wash The detection wavelength is 210 nm, the purpose peak is collected, and the component compound QJZ-9 is obtained after drying, and blown dry at 60 in a blast drying oven for the next step of isolation and purification;
(5) take the QJZ-9 component obtained in step (4) to dissolve all with a mobile phase, said mobile phase is mobile phase A or mobile phase B or a combination of the two, the separation is carried out by a preparative liquid chromatography column (two-dimensional liquid chromatography), and elution separation is carried out using a binary mobile phase system, said mobile phase A and mobile phase B are used in a combination of n-hexane, ethyl acetate, ethanol, dichloromethane, methanol, or one or a combination of several of them , elution mode isocratic elution, detection wavelength of 210 nm, collection of the target peak, after drying to obtain the component compounds QJZ-9-2, 60 blast drying oven blow-drying, QJZ-9-2 for the final target monomer polycyclic diterpene alcohol ester compounds. |
| | Euphorbia factor L9 Preparation Products And Raw materials |
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