4-Amino-7H-pyrrolo[2,3-d]pyrimidine

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Suppliers list

Company Name:	Hefei Xiuhe Biotechnology Co. Ltd. Gold
Tel:	0551-62887095 13856031416
Email:	2968933435@qq.com

Company Name:	Nanbu County Chengxin Technology Co., Ltd.
Tel:	0838-5675166 15883665058
Email:	nbcxkj@126.com

Company Name:	ChemFuture PharmaTech (Jiangsu) Ltd
Tel:	5108538618
Email:	suger.wang@chemfuture.com

4-Amino-7H-pyrrolo[2,3-d]pyrimidine manufacturers

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Basic information

Product Name:	4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Synonyms:	6-AMino-7-deazapurine 97%;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-Amino-7-deazapurine;7-DEAZAADENINE;4-AMINOPYRROLO[2,3-D]PYRIMIDINE;4-Amino-7H-pyrrolo[2,3-d]pyrimidine;3-d)pyrimidine,4-amino-7h-pyrrolo(;6-Amino-7-deazapurine;1H-Pyrrolo[2,3-d]pyrimidin-4-amine (9CI)
CAS:	1500-85-2
MF:	C6H6N4
MW:	134.14
EINECS:
Product Categories:	Heterocycle-Pyrimidine series;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Purines;Heterocycles series;Amines;Fused Ring Systems;PYRIMIDINE
Mol File:	1500-85-2.mol

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties

Melting point	257-262℃
Boiling point	318.3±45.0 °C(Predicted)
density	1.61±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	13.38±0.20(Predicted)
form	Solid
color	White to pale brown
Sensitive	Moisture & Light Sensitive
InChI	InChI=1S/C6H6N4/c7-5-4-1-2-8-6(4)10-3-9-5/h1-3H,(H3,7,8,9,10)
InChIKey	PEHVGBZKEYRQSX-UHFFFAOYSA-N
SMILES	C1=NC(N)=C2C=CNC2=N1
CAS DataBase Reference	1500-85-2(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1/PG 1
WGK Germany	2
RTECS	UY8850000
HazardClass	IRRITANT
PackingGroup	Ⅲ
HS Code	2933599590
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral
Toxicity	mouse,LD50,intraperitoneal,300mg/kg (300mg/kg),Gann. Japanese Journal of Cancer Research. Vol. 56, Pg. 219, 1965.

MSDS Information

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Usage And Synthesis

Application	6-Amino-7-azapurine is a purine biological intermediate that can be used as a chemical raw material and pharmaceutical intermediate.
Synthesis	A mixture of 5-ethynylpyrimidine-4,6-diamine (300mg, 2.24mmol), Cs2CO3 (1.46g, 4.47mmol) and DMSO (4.00ml) in a 10.00ml microwave tube was irradiated at 100W and 180°C for 15minutes. After this time, the reaction mixture was cooled to room temperature and poured into a separating funnel containing 100ml water and 100ml ethyl acetate. The aqueous layer was extracted with EtOAc (2×100ml). The combined organic extracts were dried with MgSO4 and filtered through celite, and excess solvent was removed in vacuo. Purification by column chromatography (80% EtOAc/hexane – 10% MeOH/CH2Cl2) gave 7H-pyrrolo[2,3-d]pyrimidin-4-amine (4-Amino-7H-pyrrolo[2,3-d]pyrimidine) (0.15g, 50%) as an off-white solid[1].
References	[1] Dr. Tswene D. Seanego. “7H-Pyrrolo[2,3-d]pyrimidine-4-amines as Potential Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinases.” ChemMedChem 17 22 (2022).

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials	4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol-->Nickel
Preparation Products	5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine-->7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-methyl- (9CI)

Tag:4-Amino-7H-pyrrolo[2,3-d]pyrimidine(1500-85-2) Related Product Information

Pyrimidine N-Ethylmethylamine Triethanolamine Dibenzylamine 6-Aminocaproic acid N-Methyl-2-pyrrolidone Bis(2-ethylhexyl)amine 4-Aminopyrimidine Tris(hydroxymethyl)aminomethane Triethylamine Glycine Polyvinylpyrrolidone Aminoethoxyvinyl glycine hydrochloride SANGIVAMYCIN Methyl 4-amino-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate 4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol Methyl-2-pyrrolidone 7-Deaza-2'-deoxyadenosine-5'-triphosphate lithium salt