2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester

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2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester Basic information
Product Name:2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester
Synonyms:THP-CH3-ethyl propionate;Propanoic acid, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, ethyl ester
CAS:3539-40-0
MF:C10H18O4
MW:202.25
EINECS:
Product Categories:
Mol File:3539-40-0.mol
2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester Structure
2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester Chemical Properties
Boiling point 76-81 °C(Press: 0.5 Torr)
density 1.05±0.1 g/cm3(Predicted)
Safety Information
MSDS Information
2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester Usage And Synthesis
UsesTHP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-[(Tetrahydropyran-2-yl)oxy]propionic acid ethyl ester Preparation Products And Raw materials
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