| Company Name: |
Shanghai Saikerui Biotechnology Co. , Ltd.
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| Tel: |
021-58000709 13120558703 |
| Email: |
sales@scrbio.com |
| Products Intro: |
Product Name:5'-Phosphoguanylyl-(3',5')-guanosine
CAS:33008-99-0
Purity:95%+ Package:1mg;5mg;10mg
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| Company Name: |
Shanghai meikai technology co., ltd
|
| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:5-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)tetrahydrofuran-2-yl)-3-methyl-6-((triisopropylsilyl)ethynyl)pyridin-2-yl pivalate
CAS:33008-99-0
Purity:95%
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| | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine Basic information |
| Product Name: | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine | | Synonyms: | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine;5'-Phosphoguanylyl-(3'->5')-guanosine;Guanosine, 5'-O-phosphonoguanylyl-(3'→5')-;5'-Phosphoguanylyl-(3',5')-guanosine;5'-Phosphoguanylyl-(3'->5')-guanosine sodium;5-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)tetrahydrofuran-2-yl)-3-methyl-6-((triisopropylsilyl)ethynyl)pyridin-2-yl pivalate;pGpG | | CAS: | 33008-99-0 | | MF: | C20H26N10O15P2 | | MW: | 708.43 | | EINECS: | | | Product Categories: | | | Mol File: | 33008-99-0.mol |  |
| | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine Chemical Properties |
| density | 2.60±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 1.37±0.50(Predicted) | | form | Solid | | color | White to off-white |
| | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine Usage And Synthesis |
| Uses | 5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2]. | | Biological Activity | 5’-Phosphoguanylyl-(3’,5’)-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5’-Phosphoguanylyl-(3’,5’)-guanosine can be used to detect the metabolism of nucleic acids[1][2].
5’-Phosphoguanylyl-(3’,5’)-guanosine reduces the rate of c-di-GMP degradation in cell lysates and inhibits the activity of EAL-dependent PDEs (PA2133, PvrR, and purified recombinant RocR) from P. aeruginosa[2]. | | References | [1]. Nesbitt NM, et, al. Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate. Biotechnol Rep (Amst). 2015 May 5;7:30-37. [2]. Cohen D, et, al. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11359-64. |
| | 5'-O-Phosphorylguanylyl-(3'-5')-guanosine Preparation Products And Raw materials |
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