(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	18930552037
Email:	3bsc@sina.com

Company Name:	Jinan Mingya Medical Technology Co., Ltd.
Tel:	0531-85828981
Email:	864598798@qq.com

(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran manufacturers

(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran Basic information

Product Name:	(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
Synonyms:	JWH 133;6H-Dibenzo[b,d]pyran, 3-(1,1-diMethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-triMethyl-, (6aR,10aR)-;3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol;3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC;JWH 133, >=98%;(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-(6H)-dibenzo[b.d]pyrane;3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC, 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol;JW 133
CAS:	259869-55-1
MF:	C22H32O
MW:	312.49
EINECS:
Product Categories:	Cannabinoid receptor;Cannabinoids
Mol File:	259869-55-1.mol

(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran Chemical Properties

Boiling point	382.0±42.0 °C(Predicted)
density	0.950±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	Chloroform, Ethyl Acetate
form	Oil
color	Clear Colorless
InChI	1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1
InChIKey	YSBFLLZNALVODA-RBUKOAKNSA-N
SMILES	[H][C@@]1(CC(C)=CC2)[C@@]2(C(C)(OC3=C1C=CC(C(C)(CCC)C)=C3)C)[H]

Safety Information

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

MSDS Information

(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran Usage And Synthesis

Uses	JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1'',1''-Dimethylbutyl)-1-deoxy-Δ8-THC analogs.
Definition	ChEBI: JWH-133 is a dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. It has a role as a CB2 receptor agonist, an antineoplastic agent, a vasodilator agent, an anti-inflammatory agent, an apoptosis inhibitor, an analgesic and an opioid analgesic. It is a dibenzopyran, an organic heterotricyclic compound and a benzochromene.
Biological Activity	Potent CB 2 selective agonist (K i = 3.4 nM). Approx. 200-fold selective over CB 1 receptors. Active in vivo , reducing spasticity in a murine model of multiple sclerosis. Also available in water soluble emulsion ((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran ).
storage	Store at -20°C

(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran Preparation Products And Raw materials

Tag:(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran(259869-55-1) Related Product Information

tert-Butylhydroquinone (6aR,10aR)-6a,7,10,10a-Tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol hydrochloride (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran HU-210 Ajulemic acid L-759,633