|
|
| | Carboxy Fluorescein-PEG12-NHS Basic information |
| | Carboxy Fluorescein-PEG12-NHS Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| | Carboxy Fluorescein-PEG12-NHS Usage And Synthesis |
| Description | Carboxy Fluorescein-PEG12-NHS is a fluorescein labeled PEG linker containing a NHS group, which enables labeling for antibodies and other purified proteins at primary amines (lysine side chains). The hydrophilic PEG spacer arm increases solubility in aqueous media. | | Uses | Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Carboxy Fluorescein-PEG12-NHS Preparation Products And Raw materials |
|