4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide 基本信息
| 中文名称 | 4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide |
|---|---|
| 中文同义词 | REGORAFENIB 杂质4;瑞戈菲尼杂质4;瑞戈非尼杂质03;4-(3-氟-4-((2-(甲基氨基甲酰基)吡啶-4-基)氨基)苯氧基)-N-甲基吡啶酰胺;瑞戈非尼杂质69;瑞戈非尼杂质263;瑞戈非尼杂质03-甲酸盐 |
| 英文名称 | 4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide |
| 英文同义词 | 4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide;2-Pyridinecarboxamide, 4-[3-fluoro-4-[[2-[(methylamino)carbonyl]-4-pyridinyl]amino]phenoxy]-N-methyl-;Regorafenib Dipyrimidine;4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide formate;Regorafenib Impurities69;Azilsartan medoxomil impurity263;Regorafenib Impurities04;Regorafenib Impurities11 |
| CAS号 | 1855006-12-0 |
| 分子式 | C20H18FN5O3 |
| 分子量 | 395.39 |
| EINECS号 | |
| 相关类别 | 杂质对照品;180-瑞戈非尼 |
| Mol文件 | 1855006-12-0.mol |
| 结构式 | ![4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide 结构式](CAS/20180601/GIF/1855006-12-0.gif) |
4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide 性质
| 沸点 | 631.8±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.329±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 酸度系数(pKa) | 13.92±0.46(Predicted) |
| InChIKey | USLJNRHZMUHXEP-UHFFFAOYSA-N |
| SMILES | Fc1c(ccc(c1)Oc3cc(ncc3)C(=O)NC)Nc2cc(ncc2)C(=O)NC |
安全信息
| WGK Germany | WGK 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |