XJ735

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XJ735 Suppliers list
Company Name: Alabiochem Tech.Co., Ltd.  
Tel: 512-58900862 400-0707518
Email: sales@alabiochem.com
Company Name: GL Biochem (Shanghai) Ltd  
Tel: 21-61263452 13641803416
Email: ymbetter@glbiochem.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Email: shchemsky@sina.com
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
XJ735 Basic information
Product Name:XJ735
Synonyms:CYCLO(-ALA-ARG-GLY-ASP-3-AMINOMETHYLBENZOYL) TFA;CYCLO(-ALA-ARG-GLY-ASP-3-AMINOMETHYLBENZOYL) TRIFLUOROACETATE SALT;XJ735;XJ735 TRIFLUOROACETATE SALT;CYCLO(ALA-ARG-GLY-ASP-3-AMINOMETHYL-*BENZOYL)TRIFLU;cyclo(ala-arg-gly-asp-3-aminomethylbenzoyl);Cyclo[L-alanyl-L-arginylglycyl-L-α-aspartyl-3-(aminomethyl)benzoyl];Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) >=96% (HPLC)
CAS:153381-95-4
MF:C23H32N8O7
MW:532.55
EINECS:
Product Categories:
Mol File:153381-95-4.mol
XJ735 Structure
XJ735 Chemical Properties
density 1.53±0.1 g/cm3(Predicted)
storage temp. -20°C
pka4.02±0.10(Predicted)
form powder
color white
SequenceCyclo(Ala-Arg-Gly-Asp-{Oaa})
InChIKeyHRASXYOWQQTBAQ-RCBQFDQVSA-N
SMILESC[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2
Safety Information
Safety Statements 22-24/25
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
XJ735 Usage And Synthesis
UsesCyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research[1].
Biochem/physiol ActionsCyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.
References[1] Liukun Meng et al. Osteopontin plays important roles in pulmonary arterial hypertension induced by systemic-to-pulmonary shunt. FASEB J. 2019 Jun;33(6):7236-7251. DOI:10.1096/fj.201802121RR
XJ735 Preparation Products And Raw materials
Tag:XJ735(153381-95-4) Related Product Information
XJ735 Benzoic acid, 4-[[(2S)-5-[(aminoiminomethyl)amino]-2-(benzoylamino)-1-oxopentyl]amino]-, hydrochloride (1:1) Bz-Ala-Arg-OH L-Arginine, N2-[N-(N-benzoyl-L-phenylalanyl)-L-alanyl]- (9CI) Bz-Arg-4-abz-OH hydrochloride salt Cyclo (Arg-Gly-Asp-D-Phe-Lys)