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Ethyl 5-methoxyindole-2-carboxylate

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Ethyl 5-methoxyindole-2-carboxylate manufacturers

Ethyl 5-methoxyindole-2-carboxylate Basic information
Product Name:Ethyl 5-methoxyindole-2-carboxylate
Synonyms:5-methoxy-indole-2-carboxylicaciethylester;ethyl5-methoxy-2-indolecarboxylate;methoxy-5indolecarboxylated’ethyle-2;5-METHOXYINDOLE-2-CARBOXYLIC ACID ETHYL ESTER;5-METHOXY-2-CARBETHOXYINDOLE;5-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER;ETHYL 5-METHOXYL-1H-INDOLE-2-CARBOXYLATE;2-CARBETHOXY-5-METHOXYINDOLE
CAS:4792-58-9
MF:C12H13NO3
MW:219.24
EINECS:
Product Categories:Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;Indoles;Indoles and derivatives
Mol File:4792-58-9.mol
Ethyl 5-methoxyindole-2-carboxylate Structure
Ethyl 5-methoxyindole-2-carboxylate Chemical Properties
Melting point 154-157°C
Boiling point 380.2±22.0 °C(Predicted)
density 1.216±0.06 g/cm3(Predicted)
storage temp. -20°C
form crystalline
pka14.72±0.30(Predicted)
color yellow to orange
Water Solubility Insoluble in water.
BRN 178104
InChIInChI=1S/C12H13NO3/c1-3-16-12(14)11-7-8-6-9(15-2)4-5-10(8)13-11/h4-7,13H,3H2,1-2H3
InChIKeyNPIUAXNFAUGNHP-UHFFFAOYSA-N
SMILESN1C2=C(C=C(OC)C=C2)C=C1C(OCC)=O
CAS DataBase Reference4792-58-9(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS NL6010000
HazardClass IRRITANT
Storage Class13 - Non Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Ethyl 5-methoxyindole-2-carboxylate Usage And Synthesis
UsesIt is reactant for preparation of ligands with binding specificity towards the GABA receptor, sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes, anticancer agents,integrase strand-transfer inhibitors (INSTIs),inhibitor of Proliferation of Colon Cancer Cells ,isomeridianin G as GSK-3 inhibitors, HIV-1 integrase inhibitors and inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).
Ethyl 5-methoxyindole-2-carboxylate Preparation Products And Raw materials
Preparation Products4-Bromo-5-methoxy-1H-indole-2-carboxylic acid-->Ethyl 5-hydroxyindole-2-carboxylate
Tag:Ethyl 5-methoxyindole-2-carboxylate(4792-58-9) Related Product Information
Ethyl 5-(trifluoromethoxy)indole-2-carboxylate Ethyl 5-benzyloxyindole-2-carboxylate Ethyl 5-methoxyindole-2-carboxylate 5-Methoxyindole-2-carboxylic acid 5-Methoxyindole Ethyl 6-amino-5-methoxyindole-2-carboxylate Alpertine Ethyl 5,6-dimethoxyindole-2-carboxylate Ethyl 5-acetoxyindole-2-carboxylate 3-Formyl-5-methoxy-1H-indole-2-carboxylic acid ethyl ester 3-Amino-5-methoxy-1H-indole-2-carboxylic acid ethyl ester 5-Ethoxy-1H-indole-2-carboxylic acid ethyl ester 3-AMINO-5,6-DIMETHOXY-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER AKOS JY2083359 AKOS JY2082684 3-Hydroxy-5-methoxy-1H-indole-2-carboxylic acid ethyl ester 5-Methoxy-3-methyl-1H-indole-2-carboxylic acid ethyl ester 1H-Indole-2-carboxylic acid,5-ethoxy-3-formyl-,ethyl ester