- Opipramol
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2026-06-11
- CAS:315-72-0
- Purity: 99.98%
- Supply Ability: 10g
- OPIPRAMOL
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- $1.00
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2024-05-21
- CAS:315-72-0
- Min. Order: 1G
- Purity: 99%
- Supply Ability: 1KG
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| | OPIPRAMOL Basic information |
| Product Name: | OPIPRAMOL | | Synonyms: | NSC 169867;OPIPRAMOL;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol;N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene;1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-;4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL;G-33040;GR-33040 | | CAS: | 315-72-0 | | MF: | C23H29N3O | | MW: | 363.5 | | EINECS: | 206-254-0 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 315-72-0.mol |  |
| | OPIPRAMOL Chemical Properties |
| Melting point | 100-1010C | | Boiling point | 494.88°C (rough estimate) | | density | 1.0920 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | -20°C Freezer | | solubility | Acetonitrile: slightly soluble; Chloroform: slightly soluble; Methanol: slightly soluble | | pka | pKa 8(H2O,t =25,I=0.01(NaCl)) (Uncertain) | | form | Solid | | color | Light yellow to yellow | | BRN | 627076 | | Major Application | forensics and toxicology
veterinary | | InChI | 1S/C23H29N3O/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26/h1-4,6-11,27H,5,12-19H2 | | InChIKey | YNZFUWZUGRBMHL-UHFFFAOYSA-N | | SMILES | OCCN(CC1)CCN1CCCN2C(C=CC=C3)=C3C=CC4=C2C=CC=C4 |
| Hazard Codes | Xn,N | | Risk Statements | 22-50/53 | | Safety Statements | 60-61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 1 | | RTECS | TL8750000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| | OPIPRAMOL Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Originator | Insidon,Geigy,W. Germany,1962 | | Uses | Antidepressant; antipsychotic | | Definition | ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine. | | Manufacturing Process | A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C. | | Therapeutic Function | Antidepressant, Antipsychotic |
| | OPIPRAMOL Preparation Products And Raw materials |
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