- CARBOSTYRIL 124
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- $1.10 / 1g
-
2022-03-09
- CAS:19840-99-4
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons
- CARBOSTYRIL 124
-
- $15.00 / 1KG
-
2021-07-13
- CAS:19840-99-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- CARBOSTYRIL 124
-
- $15.00 / 1KG
-
2021-07-10
- CAS:19840-99-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | CARBOSTYRIL 124 Basic information |
| | CARBOSTYRIL 124 Chemical Properties |
| Melting point | >275°C (dec.) | | Boiling point | 417.6±45.0 °C(Predicted) | | density | 1.223±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 11.45±0.70(Predicted) | | color | Off-White to Light Beige | | Appearance | Off-white to light beige solid | | λmax | 350 nm | | EPA Substance Registry System | 2(1H)-Quinolinone, 7-amino-4-methyl- (19840-99-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | CARBOSTYRIL 124 Usage And Synthesis |
| Description | Suitable as a laser dye. Dyes and metabolites. | | Chemical Properties | Off-White to Tan Solid | | Uses | Suitable as a laser dye | | General Description | Carbostyril 124 (CS124) is a chromophore that can be used as a laser dye for sensitization and optical detection. It acts as an antenna molecule that facilitates the light absorption and enhances fluorescence efficiency. | | Synthesis | GENERAL PROCEDURE: Isophthalamide (1.0 g, 9.3 mmol) was added to ethyl acetoacetate (1.2 eq, 2-3.6 g) and the mixture was heated to reflux for 20 hours. After completion of the reaction, the mixture was poured into ice (100 g) and the precipitate was collected by filtration. Purification by silica gel column chromatography (100-200 mesh, eluent methanol/chloroform, 1:99 v/v) afforded 7-amino-4-methylquinolin-2(1H)-one. | | References | [1] Medicinal Chemistry Research, 2013, vol. 22, # 11, p. 5227 - 5235
[2] Medicinal Chemistry Research, 2010, vol. 19, # 2, p. 193 - 209
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 4, p. 1624 - 1638
[4] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8712 - 8728
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 4, p. 1648 - 1653 |
| | CARBOSTYRIL 124 Preparation Products And Raw materials |
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