| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
|
| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:PDCD4 antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
|
| Company Name: |
CUSABIO TECHNOLOGY LLC
|
| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:PDCD4 Antibody
|
| Company Name: |
Hubei Serenity BioSolutions Co., Ltd.
|
| Tel: |
027-19371278702 18008634902 |
| Email: |
19384116026@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal PDCD4 Antibody
Package:20μl;50μl;100μl
|
| Company Name: |
GeneTex, Inc.
|
| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Products Intro: |
Product Name:PDCD4 antibody
|
| Company Name: |
NSJ Bioreagents
|
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Products Intro: |
Product Name:PDCD4 Antibody
|
|
| | PDCD4 ANTIBODY Chemical Properties |
| | PDCD4 ANTIBODY Usage And Synthesis |
| Applications | PDCD4 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:1,000~ 3,000. Recommended starting dilution is 1:2,000. | | Immunogen | Anti-human PDCD4 mAb is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD4 amino acids 1-469 purified from E. coli. | | Background | PDCD4 is restricted to the nucleus in proliferating cells. Expression of PDCD4 is modulated by cytokines in natural killer and T cells. PDCD4 takes part in apoptosis. PDCD4 is a translation inhibitor targeted for degradation during tumor promotion. PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. PDCD4 is swiftly phosphorylated by S6K1 kinase protein & afterwords degraded by ubiquitin ligase SCF in response to mitogens. PDCD4 in response to mitogens allows competent protein synthesis & cell growth. PDCD4 is a proapoptotic protein involved in TGF-beta1-induced apoptosis in human HCC cells, and a tumor suppressor in hepatocarcinogenesis. PDCD4 restraines tumor progression in colon carcinoma cells by the novel mechanism of down-regulating MAP4K1 transcription, with consequent inhibition of c-Jun activation and AP-1-dependent transcri |
| | PDCD4 ANTIBODY Preparation Products And Raw materials |
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