| Company Name: |
Birdo (Shanghai) Medical Technology Co., Ltd.
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| Tel: |
021-58099077-8041 18601625411 |
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sales@birdotech.com |
| Products Intro: |
Product Name:7-oxaspiro[3.5]nonan-2-amine
CAS:1374658-89-5
Purity:98% Package:5g;10g Remarks:AC268648
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| | 7-oxaspiro[3.5]nonan-2-amine Basic information |
| | 7-oxaspiro[3.5]nonan-2-amine Chemical Properties |
| Boiling point | 228.5±40.0 °C(Predicted) | | density | 1.04±0.1 g/cm3(Predicted) | | pka | 10.52±0.20(Predicted) |
| | 7-oxaspiro[3.5]nonan-2-amine Usage And Synthesis |
| Synthesis | The synthetic route for 7-oxaspiro[3.5]nonan-2-amine typically uses the corresponding ketone compound 7-oxaspiro[3.5]nonane-2-one as a key intermediate. First, a ketone with an oxaspiro[3.5]nonane skeleton is constructed via a multi-step organic synthesis, where the four-membered oxaspirobutane ring and the six-membered tetrahydropyran ring are linked by a common carbon atom. After obtaining the ketone intermediate, the final amine compound is obtained through reductive amination: 7-oxaspiro[3.5]nonane-2-one reacts with an ammonia source (e.g., ammonium acetate or liquid ammonia) in a suitable solvent to generate an imine intermediate. This imine intermediate is then reduced with a reducing agent (e.g., sodium borohydride or sodium triacetoxyborohydride) to convert the ketone group (C=O) to a primary amine group (C-NH2), thus yielding the target product 7-oxaspiro[3.5]nonan-2-amine. |
| | 7-oxaspiro[3.5]nonan-2-amine Preparation Products And Raw materials |
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