R-(+)-2-Trifluoromethyloxirane

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R-(+)-2-Trifluoromethyloxirane manufacturers
R-(+)-2-Trifluoromethyloxirane Basic information
Product Name:R-(+)-2-Trifluoromethyloxirane
Synonyms:R-(+)-2-TRIFLUOROMETHYLOXIRANE, 97;(2R)-2-(Trifluoromethyl)oxirane (ee);(2R)-(+)-3,3,3-Trifluoro-1,2-propenoxide;(2R)-2-(Trifluoromethyl)oxirane, (2R)-1,2-Epoxy-3,3,3-trifluoropropane;Oxirane, 2-(trifluoromethyl)-, (2R)-;(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane;(2R)-2-(trifluoromethyl)oxirane;R-(+)-2-Trifluoromethyloxirane
CAS:143142-90-9
MF:C3H3F3O
MW:112.05
EINECS:
Product Categories:
Mol File:143142-90-9.mol
R-(+)-2-Trifluoromethyloxirane Structure
R-(+)-2-Trifluoromethyloxirane Chemical Properties
Boiling point 25-32 °C
density 1.294 g/mL at 25 °C
refractive index n20/D <1.300
Fp -15 °F
storage temp. 2-8°C
form liquid
color Clear
InChIInChI=1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1
InChIKeyAQZRARFZZMGLHL-UWTATZPHSA-N
SMILESO1C[C@@H]1C(F)(F)F
Safety Information
Hazard Codes F+
Risk Statements 12
Safety Statements 3
RIDADR UN 1993 3/PG 1
WGK Germany 3
HS Code 2910900090
Storage Class3 - Flammable liquids
Hazard ClassificationsFlam. Liq. 1
MSDS Information
R-(+)-2-Trifluoromethyloxirane Usage And Synthesis
Uses(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:
  • Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
  • (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

R-(+)-2-Trifluoromethyloxirane Preparation Products And Raw materials
Raw materials3-Bromo-1,1,1-trifluoroacetone-->1,1,1-Trifluoro-2,3-epoxypropane
Preparation Products(S)-3,3,3-Trifluoropropane-1,2-diol-->1,1,1-Trifluoro-2,3-epoxypropane
Tag:R-(+)-2-Trifluoromethyloxirane(143142-90-9) Related Product Information
1,1,1-Trifluoro-2,3-epoxypropane Ethylene oxide (S)-(+)-1-Methoxy-2-propanol HFPO dimer, acid fluoride POLY(PERFLUOROPROPYLENE OXIDE) 2,2-Bis(trifluoromethyl)oxirane R-(+)-2-Trifluoromethyloxirane 2,2-Difluoro-3,3-bis(trifluoromethyl)oxirane Epifluorohydrin