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| | TRH-Gly Basic information |
| Product Name: | TRH-Gly | | Synonyms: | PYR-HIS-PRO-GLY-OH;PYR-HIS-PRO-GLY;PE-H-P-G;THYROTROPIN-RELEASING HORMONE-GLY;pglu-his-pro-gly;GLP-HIS-PRO-GLY;GLP-HIS-PRO-GLY: GLP-HPG;Glycine, 5-oxo-L-prolyl-L-histidyl-L-prolyl- | | CAS: | 85344-77-0 | | MF: | C18H24N6O6 | | MW: | 420.42 | | EINECS: | | | Product Categories: | | | Mol File: | 85344-77-0.mol |  |
| | TRH-Gly Chemical Properties |
| | TRH-Gly Usage And Synthesis |
| Uses | Trh-gly (TRH-glycine) is a precursor of thyrotropin (TSH)-releasing hormone (TRH) that can release thyrotropin and prolactin[1]. | | in vivo | In urethane-anesthetized 2-month-old (250 g) male Sprague-Dawley rats, Trh-gly (intracisternal injection; 1.0 mg) leads to a significant increase in the TRH levels in hypothalamus, medulla and blood[1]. | | References | [1] A E Pekary, et al. Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: conversion to TRH is sufficient for in vivo effects. Neuroendocrinology. 1990 Dec;52(6):618-25. DOI:10.1159/000125654
[2] M Yamada, et al. Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-Gly. Neurosci Lett. 1995 Aug 18;196(1-2):109-12. DOI:10.1016/0304-3940(95)11861-p |
| | TRH-Gly Preparation Products And Raw materials |
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