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| | PYR-HIS-PRO-BETANA Basic information |
| Product Name: | PYR-HIS-PRO-BETANA | | Synonyms: | pyroglutamyl-histidyl-prolyl-2-naphthylamide;Pyr-His-Pro-bNA;TRH-bNA;PYROGLU-HIS-PRO-BETA-NAPHTHYLAMIDE;PYR-HIS-PRO-BETANA;TRH-BETANA;THYROTROPIN-RELEASING HORMONE-BETANA;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-N-2-naphthalenyl- | | CAS: | 73644-58-3 | | MF: | C26H28N6O4 | | MW: | 488.54 | | EINECS: | | | Product Categories: | | | Mol File: | 73644-58-3.mol |  |
| | PYR-HIS-PRO-BETANA Chemical Properties |
| | PYR-HIS-PRO-BETANA Usage And Synthesis |
| Uses | TRH-βNA is a substrate for determining the membrane TRH-deamidating enzyme (TRH-DE) activity and membrane pyroglutamyl aminopeptidase II (PPII) activity[1][2]. | | References | [1] Müller-Fielitz H, et al. Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis. Nat Commun. 2017 Sep 7;8(1):484. DOI:10.1038/s41467-017-00604-6
[2] Alvarez-Salas E, et al. Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. Endocrinology. 2012 Aug;153(8):4067-76. DOI:10.1210/en.2011-2011 |
| | PYR-HIS-PRO-BETANA Preparation Products And Raw materials |
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