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| | 4-FLUOROBENZYL ISOCYANATE Basic information |
| | 4-FLUOROBENZYL ISOCYANATE Chemical Properties |
| Boiling point | 211 °C(lit.) | | density | 1.186 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.505(lit.) | | Fp | 199 °F | | storage temp. | -20°C | | form | Liquid | | color | Colorless | | Sensitive | Lachrymatory | | InChI | 1S/C8H6FNO/c9-8-3-1-7(2-4-8)5-10-6-11/h1-4H,5H2 | | InChIKey | HHSIWJYERNCLKQ-UHFFFAOYSA-N | | SMILES | Fc1ccc(CN=C=O)cc1 |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36/37/39 | | RIDADR | UN 2206 6.1/PG 3 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29291090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 |
| | 4-FLUOROBENZYL ISOCYANATE Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | 4-Fluorobenzyl isocyanate may be used as a reagent in the synthesis of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide and (S)-2-(4-fluorobenzyl)-7-hydroxy-10,10a-dihydroimidazo[1,5-b]isoquinoline-1,3(2H,5H)-dione. | | General Description | 4-Fluorobenzyl isocyanate, also known as 1-fluoro-4-(isocyanatomethyl)benzene, is an organic building block containing an isocyanate group. | | Synthesis | To a 100 mL round bottom flask was added benzylamine (4 mmol, 800 mg) and toluene (10 mL), triphosgene (5 mmol, 1.5 g) was added with stirring and the reaction was carried out at reflux for 4 hours. The solvent was removed by concentration, after which dichloromethane (5 mL) was added to give 3-diexamethylene Tsuen-1-propanamine. |
| | 4-FLUOROBENZYL ISOCYANATE Preparation Products And Raw materials |
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