| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
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| Tel: |
021-51320588 |
| Email: |
tauto@tautobiotech.com |
| Products Intro: |
Product Name:Skyrin
CAS:602-06-2
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CN2-0001-M001
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- Skyrin
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- $0.10 / 1G
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2026-02-02
- CAS:602-06-2
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 20KG
- Skyrin
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- $458.00 / 1mg
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2025-12-22
- CAS:602-06-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| Product Name: | Skyrin | | Synonyms: | 4',4''',5,5'',7,7''-HEXAHYDROXY-3''',8-BIFLAVONE;3',8''-BIAPIGENIN;DIDEMETHYL-GINKGETIN;I3,II8 BIAPIGENIN;Endothianin;Skirin;skyrin;(+)-2,2',4,4',5,5'-Hexahydroxy-7,7'-dimethyl-1,1'-bianthracene-9,9',10,10'-tetrone | | CAS: | 602-06-2 | | MF: | C30H18O10 | | MW: | 538.46 | | EINECS: | | | Product Categories: | | | Mol File: | 602-06-2.mol |  |
| | Skyrin Chemical Properties |
| Melting point | >380℃ | | Boiling point | 956.1±65.0 °C(Predicted) | | density | 1.698±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble | | form | A crystalline solid | | pka | 5.24±0.20(Predicted) | | color | Orange to dark red | | biological source | Penicillium islandicum | | InChI | 1S/C30H18O10/c1-9-3-11-19(13(31)5-9)29(39)23-17(35)7-15(33)21(25(23)27(11)37)22-16(34)8-18(36)24-26(22)28(38)12-4-10(2)6-14(32)20(12)30(24)40/h3-8,31-36H,1-2H3 | | InChIKey | MQSXZQXHIJMNAF-UHFFFAOYSA-N | | SMILES | Oc1c2c(c(c(c1)O)c4c5c(c(cc4O)O)C(=O)c6c(cc(cc6O)C)C5=O)C(=O)c3c(c(cc(c3)C)O)C2=O |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10 | | Storage Class | 11 - Combustible Solids |
| | Skyrin Usage And Synthesis |
| Uses | Skyrin is a non-peptidic anthraquinone, mycotoxin. | | Definition | ChEBI: Skyrin is a biaryl and a trihydroxyanthraquinone. It is functionally related to an emodin. | | Biological Activity | Skyrin is a non-peptidic anthraquinone, mycotoxin with in vitro cytotoxic activity. It suppresses the growth of HeLa, Vero, K562, Raji, Wish and Calu-1 cell lines. Skyrin treatment induces DNA fragmentation and other morphological changes leading to apoptosis in Human HL-60 promyelotic leukemia cells. Skyrin was found to serve as an anti-diabetic agent by selectively binding to the glucagon receptor acting as its antagonist. Regular binding of glucagon to its receptor on hepathocyte plasma membrane activates adenylate cyclase indirectly. As a result, the cAMP produced activates protein kinase A with a consequent increase in both glycogen breakdown and gluconeogenesis leading to glucose output. Skyrin was shown to block this signal transduction sequence, such th at the interaction of glucagons with its receptor does not result in an increase in cAMP production. Skyrin was also found to efficiently scavenge free radical species as OH, R and of singlet oxygen (1O2). Based on Skyrin selective toxicity towards insect cell line Sf9, it may be useful as an agent for pest control. | | storage | +4°C |
| | Skyrin Preparation Products And Raw materials |
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