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| | 2-Hexadecanoylthio-1-ethylphosphorylcholine Basic information |
| Product Name: | 2-Hexadecanoylthio-1-ethylphosphorylcholine | | Synonyms: | 4-OXIDE-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-3,5-DIOXA-8-THIA-4-PHOSPHATETRACOSAN-1-AMINIUM, INNER SALT;HEPC;thioglycollecithin;BDPQVGIMLZYZQA-UHFFFAOYSA-N;2-Hexadecanoylthio-1-ethylphosphorylcholine | | CAS: | 60793-01-3 | | MF: | C23H48NO5PS | | MW: | 481.67 | | EINECS: | | | Product Categories: | | | Mol File: | 60793-01-3.mol |  |
| | 2-Hexadecanoylthio-1-ethylphosphorylcholine Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Ethanol: 30 mg/ml; PBS (pH 7.2): 5 mg/ml |
| | 2-Hexadecanoylthio-1-ethylphosphorylcholine Usage And Synthesis |
| Description | Thioester analogs of glycerophospholipids, in combination with Ellman’s reagent, are convenient colorimetric substrates for the measurement of phospholipase activity. HEPC is a truncated analog of phosphatidylcholine with the entire sn-1 substituent deleted, and with a hexadecylthioester in the sn-2 position.1 HEPC is a substrate for Type II phospholipase A2 (PLA2) enzymes, such as porcine pancreatic, bee venom, and snake venom PLA2. The intrinsic biological activity of HEPC has not been actively investigated. | | Uses | 2-Hexadecanoylthio-1-ethylphosphorylcholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | | Definition | ChEBI: 2-hexadecanoylthio-1-ethylphosphorylcholine is a member of phosphocholines. | | References | 1. Bhat, M.K., Mueller-Harvey, I., Sumner, I.G., et al. Simplified methods for the synthesis of 2-hexadecanoylthio-1-ethylphosphorylcholine and for the determination of phospholipase A2 activity Biochim. Biophys. Acta 1166,244-250(1993). |
| | 2-Hexadecanoylthio-1-ethylphosphorylcholine Preparation Products And Raw materials |
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