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| | PROPYNAL Basic information |
| Product Name: | PROPYNAL | | Synonyms: | PROPYNAL;PROPIOALDEHYDE;PROPYNAL TECH.;2-Propyn-1-al;2-Propyne-1-one;Propiolic aldehyde;prop-2-ynal;Prorynal | | CAS: | 624-67-9 | | MF: | C3H2O | | MW: | 54.05 | | EINECS: | 210-857-4 | | Product Categories: | | | Mol File: | 624-67-9.mol |  |
| | PROPYNAL Chemical Properties |
| Melting point | 121-122 °C | | Boiling point | 58.85°C | | density | 0.9152 | | refractive index | 1.3963 (estimate) | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol | | form | Oil | | color | Colourless to Orange | | Stability: | Light Sensitive, Moisture Sensitive, Volatile | | EPA Substance Registry System | 2-Propynal (624-67-9) |
| Risk Statements | 10 | | Safety Statements | 16 | | RIDADR | 1989 | | TSCA | TSCA listed |
| | PROPYNAL Usage And Synthesis |
| Uses | 2-Propynal is hypothesized to be a possible metabolite of pargyline, a monoamine oxidase inhibitor that is used as an antihypertensive agent. 2-Propynal is also known to induce hepatocyte toxicity in vivo in rats. | | Definition | ChEBI: Prop-2-ynal is a ynal and a terminal acetylenic compound. It has a role as a mouse metabolite. | | Synthesis Reference(s) |
1. Sauer, J. C. OSC 1962, 4, 813.
2. See also: Ghelfi, F.; Grandi, R.; Pagnoni, U. M. SC 1992, 22, 1845.
| | Synthesis | Propynal is most simply synthesized by oxidation of Propargyl Alcohol.1,2
| | Enzyme inhibitor | This aldehyde (FW = 54.048 g/mol; CAS 624-67-9), also known as propynal, synthesized from propargyl alcohol, is an irreversible inhibitor of aldehyde dehydrogenases. | | storage | It is recommended that handling of propynal should include the use of a nonglass container and dilution with a sufficient volume of an inert solvent to absorb the heat of polymerization without boiling, e.g. <=10% in toluene. Use in a fume hood.
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| | PROPYNAL Preparation Products And Raw materials |
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