N,N-Diethanol amine-PEG4-Boc

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N,N-Diethanol amine-PEG4-Boc Basic information
Product Name:N,N-Diethanol amine-PEG4-Boc
Synonyms:N,N-Diethanol amine-PEG4-Boc;N,N-diethanol amine-PEG4-tert-butyl ester;4,7,10,13-Tetraoxa-16-azaoctadecanoic acid, 18-hydroxy-16-(2-hydroxyethyl)-, 1,1-dimethylethyl ester
CAS:2279944-66-8
MF:C19H39NO8
MW:409.51
EINECS:
Product Categories:
Mol File:2279944-66-8.mol
N,N-Diethanol amine-PEG4-Boc Structure
N,N-Diethanol amine-PEG4-Boc Chemical Properties
Boiling point 508.8±45.0 °C(Predicted)
density 1.096±0.06 g/cm3(Predicted)
pka14.37±0.10(Predicted)
Safety Information
MSDS Information
N,N-Diethanol amine-PEG4-Boc Usage And Synthesis
DescriptionN,N-diethanol amine-PEG4-tert-butyl ester is a PEG reagent with two hydroxyl moieties. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media.
UsesN,N-Diethanol amine-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N,N-Diethanol amine-PEG4-Boc Preparation Products And Raw materials
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