4-(4'-Bromophenyl)piperidine hydrochloride

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4-(4'-Bromophenyl)piperidine hydrochloride manufacturers

4-(4'-Bromophenyl)piperidine hydrochloride Basic information
Product Name:4-(4'-Bromophenyl)piperidine hydrochloride
Synonyms:4-(4-BROMO-PHENYL)PIPERIDINE HCL;4-(4-bromophenyl)piperidine C11H15BrClN;Piperidine,4-(4-bromophenyl)-, hydrochloride (1:1);4-(5-bromophenyl)piperidine HCl;4-(4'-Bromophenyl)piperidine hydrochloride
CAS:769944-79-8
MF:C11H14BrN.ClH
MW:276.6
EINECS:672-425-5
Product Categories:
Mol File:769944-79-8.mol
4-(4'-Bromophenyl)piperidine hydrochloride Structure
4-(4'-Bromophenyl)piperidine hydrochloride Chemical Properties
storage temp. Inert atmosphere,Room Temperature
AppearanceWhite to off-white Powder
Safety Information
MSDS Information
4-(4'-Bromophenyl)piperidine hydrochloride Usage And Synthesis
Synthesis
1-N-BOC-4-(4-BROMOPHENYL)PIPERIDINE

769944-78-7

4-(4'-BROMOPHENYL)PIPERIDINE HYDROCHLORIDE

769944-79-8

General procedure for the synthesis of 4-(4-bromophenyl)piperidine hydrochloride from 1-N-Boc-4-(4-bromophenyl)piperidine: To a solution of ethyl acetate (1 mL) containing 1-N-Boc-4-(4-bromophenyl)piperidine (1114 mg, 3.27 mmol) was slowly added a solution of ethyl acetate (2 mL) with 4 N hydrogen chloride at room temperature. The reaction mixture was stirred at room temperature for 5 h before the solvent was removed by distillation under reduced pressure. The resulting solid was washed with ethyl acetate and dried under vacuum to give 4-(4-bromophenyl)piperidine hydrochloride (884 mg, 98% yield) as a white solid.

References[1] Patent: WO2004/85408, 2004, A1. Location in patent: Page 294
4-(4'-Bromophenyl)piperidine hydrochloride Preparation Products And Raw materials
Raw materials1-N-Boc-4-(4-bromophenyl)piperidine-->Ethyl acetate-->Hydrochloric acid
Preparation Products1-N-Boc-4-(4-bromophenyl)piperidine-->Ethanone, 1-[4-(4-bromophenyl)-1-piperidinyl]-
Tag:4-(4'-Bromophenyl)piperidine hydrochloride(769944-79-8) Related Product Information
4-(4'-Bromophenyl)piperidine hydrochloride 4-(4'-Bromophenyl)piperidine