(Rac)-NMDAR antagonist 1

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(Rac)-NMDAR antagonist 1 Basic information
Product Name:(Rac)-NMDAR antagonist 1
Synonyms:(Rac)-NMDAR antagonist 1;Pyrrolo[2,1-b]quinazoline-1-carboxamide, 7-bromo-1,2,3,9-tetrahydro-N-[2-(4-hydroxyphenyl)ethyl]-
CAS:2435557-99-4
MF:C20H20BrN3O2
MW:414.3
EINECS:
Product Categories:
Mol File:2435557-99-4.mol
(Rac)-NMDAR antagonist 1 Structure
(Rac)-NMDAR antagonist 1 Chemical Properties
density 1.54±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 5 mg/mL (12.07 mM)
pka10.01±0.15(Predicted)
form Solid
color White to gray
Water Solubility Water: < 0.1 mg/mL (insoluble)
Safety Information
MSDS Information
(Rac)-NMDAR antagonist 1 Usage And Synthesis
Uses(Rac)-NMDAR antagonist 1 is the racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective NMDAR antagonist[1].
References[1] Zhang L, et al. Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents. Eur J Med Chem. 2018 May 10;151:27-38. DOI:10.1016/j.ejmech.2018.03.052
(Rac)-NMDAR antagonist 1 Preparation Products And Raw materials
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