| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:WRR139
CAS:2138924-36-2
Package:1removed
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Benzenebutanamide, N-(3-methylbutyl)-α-[[3-[(4-methylphenyl)sulfonyl]-1-oxo-2-propen-1-yl]amino]-, (αS)- manufacturers
- WRR139
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- $762.00
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2026-07-04
- CAS:2138924-36-2
- Purity:
- Supply Ability: 10g
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| | Benzenebutanamide, N-(3-methylbutyl)-α-[[3-[(4-methylphenyl)sulfonyl]-1-oxo-2-propen-1-yl]amino]-, (αS)- Basic information |
| | Benzenebutanamide, N-(3-methylbutyl)-α-[[3-[(4-methylphenyl)sulfonyl]-1-oxo-2-propen-1-yl]amino]-, (αS)- Chemical Properties |
| Boiling point | 724.4±60.0 °C(Predicted) | | density | 1.153±0.06 g/cm3(Predicted) | | pka | 12.63±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | Benzenebutanamide, N-(3-methylbutyl)-α-[[3-[(4-methylphenyl)sulfonyl]-1-oxo-2-propen-1-yl]amino]-, (αS)- Usage And Synthesis |
| Uses | WRR139 is a peptide vinyl sulfone involving in disease processes such as inflammation and cancer. WRR139 is also a cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1 inhibitor. WRR139 enhances Carfilzomib cytotoxicity against cancer cells[1]. | | References | [1] Tomlin FM, et al. Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity. ACS Cent Sci. 2017 Nov 22;3(11):1143-1155. DOI:10.1021/acscentsci.7b00224 |
| | Benzenebutanamide, N-(3-methylbutyl)-α-[[3-[(4-methylphenyl)sulfonyl]-1-oxo-2-propen-1-yl]amino]-, (αS)- Preparation Products And Raw materials |
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