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DIHYDROCODEINE TRIFLUOROACETATE

DIHYDROCODEINE TRIFLUOROACETATE Basic information
Product Name:DIHYDROCODEINE TRIFLUOROACETATE
Synonyms:4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-alpha-o;4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6alpha-ol;6-alpha-hydrocodol;6alpha-Hydrocodol;6-Hydroxy-3-methoxy-N-methyl-4,5-epoxymorphinan;7,8-dihydro-codein;7,8-Dihydrocodeine;8,14-Dihydroneopine
CAS:125-28-0
MF:C20H24F3NO4
MW:399.4
EINECS:204-732-3
Product Categories:
Mol File:125-28-0.mol
DIHYDROCODEINE TRIFLUOROACETATE Structure
DIHYDROCODEINE TRIFLUOROACETATE Chemical Properties
Melting point 112-113°
Boiling point bp15 248°
density 1.1412 (rough estimate)
refractive index 1.5740 (estimate)
Fp 9℃
storage temp. 2-8°C
solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form A neat solid
EPA Substance Registry SystemMorphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5?,6?)- (125-28-0)
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 7-16-36/37-45
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
MSDS Information
DIHYDROCODEINE TRIFLUOROACETATE Usage And Synthesis
DescriptionDihydrocodeine (Item No. 37884) is an analytical reference standard categorized as an opioid.1 Dihydrocodeine is an active metabolite of hydrocodone (Item Nos. ISO60144 | 15461 | 22166).2 Formulations containing dihydrocodeine have been used in the treatment of severe pain and have been associated with misuse and polypharmacy-related overdose.3 Dihydrocodeine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.
OriginatorBicodein,Uquifa
DefinitionChEBI: Dihydrocodeine is a morphinane alkaloid.
Manufacturing ProcessThe codein was reduced by hydrogen in the presence catalyst Pt (or Pd, or Ni) and 7,8-dihydrocodein was obtained.
To the 7,8-dihydrocodein tartaric acid was added and mixed, in the result 7,8- dihydrocodein bitartrate was obtained.
Therapeutic FunctionAntitussive, Narcotic analgesic
Safety ProfilePoison by ingestion, intravenous, and subcutaneous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, miosis (pupillary constriction), and respiratory depression. An analgesic. Can cause drug dependency with repeated doses. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.
DIHYDROCODEINE TRIFLUOROACETATE Preparation Products And Raw materials
Raw materialsd-Codeine-->Hydrogen-->Platinum-->D-(-)-Tartaric Acid-->HYDROCODONE-->CODEINE
Preparation ProductsHYDROCODONE BITARTRATE RELATED COMPOUND A CII (70 MG) (MORPHINAN-6-ONE, 4-HYDROXY-3-METHOXY-17-METHYL)
Tag:DIHYDROCODEINE TRIFLUOROACETATE(125-28-0) Related Product Information
CODEINE DIHYDROCODEINE-6-BETA-D-GLUCURONIDE TRIFLUOROACETATE DIHYDROCODEINE TRIFLUOROACETATE DIHYDROMORPHINE N-Propionitrile Chlorphine (hydrochloride) OXYCODONE HYDROCHLORIDE