2-Propen-1-one, 1-[3-[8-chloro-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1H-1,2,3-triazolo[4,5-c]quinolin-1-yl]-1-azetidinyl]- manufacturers
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| | 2-Propen-1-one, 1-[3-[8-chloro-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1H-1,2,3-triazolo[4,5-c]quinolin-1-yl]-1-azetidinyl]- Basic information |
| | 2-Propen-1-one, 1-[3-[8-chloro-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1H-1,2,3-triazolo[4,5-c]quinolin-1-yl]-1-azetidinyl]- Chemical Properties |
| Boiling point | 675.8±55.0 °C(Predicted) | | density | 1.62±0.1 g/cm3(Predicted) | | pka | 6.61±0.35(Predicted) |
| | 2-Propen-1-one, 1-[3-[8-chloro-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1H-1,2,3-triazolo[4,5-c]quinolin-1-yl]-1-azetidinyl]- Usage And Synthesis |
| Uses | KRAS G12C inhibitor 53 (Compound 1) is a KRAS G12C inhibitor[1]. | | IC 50 | KRAS(G12C) | | References | [1] Youxi CHEN, et al. Heterocyclic derivative and preparation method therefor and use thereof. WO2022037631A1. |
| | 2-Propen-1-one, 1-[3-[8-chloro-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1H-1,2,3-triazolo[4,5-c]quinolin-1-yl]-1-azetidinyl]- Preparation Products And Raw materials |
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